SCHEMBL3379221

SCHEMBL3379221

Cc1nnc(SN)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3791857 0.78 GAA (0.48)
SCHEMBL3729632 0.76
SCHEMBL27317175 0.74
SCHEMBL3729631 0.74
SCHEMBL19884346 0.74
SCHEMBL20177132 0.72
SCHEMBL10914515 0.72 GAA (0.44)
SCHEMBL13240158 0.72 GAA (0.59)
SCHEMBL14414190 0.70 GAA (0.43)
SCHEMBL5962495 0.70 GAA (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1557671-B1 IN VITRO METHOD OF CLINICAL DIAGNOSIS. NIHON MEDIPHYSICS CO LTD (JP) 2010-11-24 EP disclosed
WO-2009143156-A2 IMIDAZO[1,2-a]PYRIDINE COMPOUNDS SEPRACOR INC. (US) 2009-11-26 WO disclosed
WO-2008139941-A1 SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2008-11-20 WO disclosed
EP-1197227-B9 METHOD OF THE ADMINISTRATION OF DRUGS HAVING BINDING AFFINITY WITH PLASMA PROTEIN AND PREPARATION TO BE USED IN THE METHOD NIHON MEDIPHYSICS CO LTD (JP) 2008-06-11 EP disclosed
EP-1197227-B1 METHOD OF THE ADMINISTRATION OF DRUGS HAVING BINDING AFFINITY WITH PLASMA PROTEIN AND PREPARATION TO BE USED IN THE METHOD NIHON MEDIPHYSICS CO LTD (JP) 2007-09-12 EP disclosed
US-7175991-B2 Method of measuring binding site on plasma protein of plasma protein-binding drug and method of measuring plasma protein mutation NIHON MEDI-PHYSICS CO., LTD. (JP) 2007-02-13 US disclosed
US-20060166269-A1 Method of measuring binding site on plasma protein of plasma protein-binding drug and method of measuring plasma protein mutation NIHON MEDI-PHYSICS CO., LTD. (JP) 2006-07-27 US disclosed
US-20060140857-A1 Method of the administration of drugs with binding affinity for plasma protein and preparation to be used in the method NIHON MEDI-PHYSICS CO., LTD. 2006-06-29 US disclosed
US-7029653-B1 Method of the administration of drugs having binding affinity with plasma protein and preparation to be used in the method NIHON MEDI-PHYSICS CO., LTD. (JP) 2006-04-18 US disclosed
EP-1557671-A1 METHOD OF MEASURING BINDING SITE ON PLASMA PROTEIN OF PLASMA PROTEIN-BINDING DRUG AND METHOD OF MEASURING PLASMA PROTEIN MUTATION Nihon Medi-Physics Co., Ltd. (JP) 2005-07-27 EP disclosed
EP-1197227-A1 METHOD OF THE ADMINISTRATION OF DRUGS HAVING BINDING AFFINITY WITH PLASMA PROTEIN AND PREPARATION TO BE USED IN THE METHOD Nihon Medi-Physics Co., Ltd. (JP) 2002-04-17 EP disclosed