SCHEMBL337973

SCHEMBL337973

CCOC(=O)c1cc(-c2ccc(C(=O)O)c(C(=O)OCC)c2)ccc1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.53
CA12 O43570 2/20 0.53
CA1 P00915 2/20 0.53
CA2 P00918 2/20 0.53
CA7 P43166 2/20 0.53
CA9 Q16790 2/20 0.53
CA14 Q9ULX7 2/20 0.53
ALDH1A1 P00352 4/20 0.47
HSD17B10 Q99714 3/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
GAA P10253 2/20 0.47
MAPT P10636 2/20 0.47
ALOX15 P16050 2/20 0.47
RAB9A P51151 2/20 0.47
HPGD P15428 2/20 0.47
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
NPC1 O15118 1/20 0.47
LMNA P02545 1/20 0.47
MCL1 Q07820 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5886273 0.97 TSHR (0.55) TSHRCA12CA1CA2CA7
SCHEMBL6110541 0.94 TSHR (0.56) TSHRALDH1A1HSD17B10SMN1; SMN2GAA
SCHEMBL12665762 0.94 CA12 (0.47) TSHRCA12CA1CA2CA7
SCHEMBL15144236 0.91 TSHR (0.49) TSHRCA12CA1CA2CA7
SCHEMBL12665764 0.89 TSHR (0.50) TSHRCA12CA1CA2CA7
SCHEMBL12673685 0.88 CA12 (0.43) TSHRCA12CA1CA2CA7
SCHEMBL6110544 0.87 TSHR (0.61) TSHRALDH1A1HSD17B10SMN1; SMN2GAA
SCHEMBL14252251 0.86 TSHR (0.65) TSHRCA12CA1CA2CA7
SCHEMBL21710427 0.84 TSHR (0.49) TSHRCA12CA1CA2CA7
SCHEMBL16351839 0.84 TSHR (0.56) TSHRCA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1721924-B1 ENDLESS TUBULAR POLYIMIDE FILM GUNZE KK (JP) 2014-12-17 EP disclosed
US-8314204-B2 Endless tubular polyimide film GUNZE LIMITED (JP) 2012-11-20 US disclosed
US-20120040121-A1 ENDLESS TUBULAR POLYIMIDE FILM UBE INDUSTRIES, LTD. (JP) 2012-02-16 US disclosed
US-8097693-B2 Endless tubular polyimide film GUNZE LIMITED (JP) 2012-01-17 US disclosed
US-20110117431-A1 LITHIUM SECONDARY BATTERY AND METHOD OF MANUFACTURING THE SAME SANYO ELECTRIC CO., LTD. (JP) 2011-05-19 US disclosed
US-20070178264-A1 Endless tubular polyimide film GUNZE LIMITED (JP) 2007-08-02 US disclosed
EP-1721924-A1 ENDLESS TUBULAR POLYIMIDE FILM GUNZE LIMITED (JP) 2006-11-15 EP disclosed
US-20060235194-A1 Novel polymer compound, precursor for the same and thin film-forming method using the same polymer precursor KATO TAKASHI 2006-10-19 US disclosed
US-20060235184-A1 Novel polymer compound, precursor for the same and thin film-forming method using the same polymer precursor KATO TAKASHI 2006-10-19 US disclosed
US-7087311-B2 Polymer compound, precursor for the same and thin film-forming method using the same polymer precursor CHISSO CORPORATION (JP) 2006-08-08 US disclosed
US-20060019109-A1 Novel polymer compound, precursor for the same and thin film-forming method using the same polymer precursor KATO TAKASHI 2006-01-26 US disclosed
US-6949618-B2 Polymer compound, precursor for the same and thin film-forming method using the same polymer precursor CHISSO CORPORATION (JP) 2005-09-27 US disclosed
US-20030153719-A1 Novel polymer compound, precursor for the same and thin film-forming method using the same polymer precursor CHISSO CORPORATION (JP) 2003-08-14 US disclosed