Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 5/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 4/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3380833 | 0.93 | F10 (0.35) | PREPPARP1F10 | |
| SCHEMBL4244644 | 0.91 | F10 (0.35) | F10OPRM1 | |
| SCHEMBL4247278 | 0.90 | F10 (0.35) | PREPPARP1F10OPRM1 | |
| SCHEMBL3380174 | 0.88 | F10 (0.43) | F10OPRM1 | |
| SCHEMBL3382415 | 0.86 | F10 (0.38) | PARP1F10 | |
| SCHEMBL4243981 | 0.85 | F10 (0.38) | F10OPRM1 | |
| SCHEMBL4245786 | 0.85 | F10 (0.41) | F10OPRM1 | |
| SCHEMBL4245572 | 0.85 | F10 (0.35) | F10OPRM1 | |
| SCHEMBL3616876 | 0.83 | F10 (0.44) | PREPPARP1F10 | |
| SCHEMBL4250023 | 0.83 | F10 (0.42) | F10OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029586-B1 | ISOINDOLIN-1-ONE-, ISOINDOLIN-3-ONE- AND ISOINDOLIN-1,3-DIONE-DERIVATIVES AND USE THEREOF | BAYER SCHERING PHARMA AG (DE) | 2010-11-24 | — | — | EP | disclosed |
| EP-2029586-A1 | ISOINDOLIN-1-ONE-, ISOINDOLIN-3-ONE- AND ISOINDOLIN-1,3-DIONE-DERIVATIVES AND USE THEREOF | Bayer HealthCare AG (DE) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007137800-A1 | ISOINDOLIN-1-ONE-, ISOINDOLIN-3-ONE- AND ISOINDOLIN-1,3-DIONE-DERIVATIVES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2007-12-06 | — | — | WO | disclosed |