SCHEMBL338108

SCHEMBL338108

ClC(Cl)c1cccc(C(Cl)Cl)c1.N=C=O.N=C=O

nearest known ligand 0.46

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
PGK1 P00558 5/20 0.43
PGK2 P07205 5/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27716381 1.00 TSHR (0.46) TSHRPGK1PGK2
SCHEMBL631114 0.84 TSHR (0.61) TSHRPGK1PGK2
SCHEMBL11673842 0.83 TSHR (0.70) TSHR
SCHEMBL11869848 0.83 TSHR (0.70) TSHR
SCHEMBL2045779 0.76 HDAC4 (0.50) TSHRPGK1PGK2
SCHEMBL3358129 0.76 HDAC4 (0.50) TSHRPGK1PGK2
SCHEMBL31571653 0.73 TSHR (0.48) TSHR
SCHEMBL17255536 0.73 TSHR (0.48) TSHR
SCHEMBL7295518 0.73 TSHR (0.48) TSHRPGK1PGK2
SCHEMBL1539023 0.73 TSHR (0.48) TSHRPGK1PGK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8097190-B2 Optical resin composition having excellent impact resistance and method for fabricating optical lens using the same KOC SOLUTION CO., LTD. (KR) 2012-01-17 US disclosed
US-20090225425-A1 OPTICAL RESIN COMPOSITION HAVING EXCELLENT IMPACT RESISTANCE AND METHOD FOR FABRICATING OPTICAL LENS USING THE SAME SHIN DAE SPECIALTIES CO., LTD. (KR) 2009-09-10 US disclosed