Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 6/20 | 0.75 |
| ▸ | GANAB | Q14697 | 2/20 | 0.66 |
| ▸ | FUCA1 | P04066 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | GBA2 | Q9HCG7 | 3/20 | 0.55 |
| ▸ | GLA | P06280 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MGAM | O43451 | 2/20 | 0.55 |
| ▸ | LCT | P09848 | 2/20 | 0.55 |
| ▸ | SI | P14410 | 2/20 | 0.55 |
| ▸ | AGL | P35573 | 2/20 | 0.55 |
| ▸ | GBA3 | Q9H227 | 2/20 | 0.55 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.55 |
| ▸ | MAN2B2 | Q9Y2E5 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TREH | O43280 | 1/20 | 0.55 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14020234 | 0.87 | GBA1 (1.00) | GBA1GANABFUCA1GAAGBA2 | |
| SCHEMBL14020226 | 0.87 | GBA1 (1.00) | GBA1GANABFUCA1GAAGBA2 | |
| SCHEMBL2268716 | 0.87 | GBA1 (1.00) | GBA1GANABFUCA1GAAGBA2 | |
| SCHEMBL25748644 | 0.87 | GBA1 (1.00) | GBA1GANABFUCA1GAAGBA2 | |
| Hydrochloric Acid SCHEMBL14976072 | 0.85 | GBA1 (1.00) | GBA1GANABFUCA1GAAGBA2 | |
| SCHEMBL7884199 | 0.80 | — | — | |
| SCHEMBL6129774 | 0.80 | — | — | |
| SCHEMBL7894158 | 0.80 | — | — | |
| Iminoribitol SCHEMBL2340523 | 0.77 | GAA (0.79) | GBA1GANABFUCA1GAAGBA2 | |
| Deoxyfuconojirimycin SCHEMBL3381760 | 0.76 | FUCA1 (0.72) | GBA1GANABFUCA1GAAGBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010049678-A2 | TREATMENT OF ENERGY UTILIZATION DISEASES | SUMMIT CORPORATION PLC (GB) | 2010-05-06 | — | — | WO | disclosed |