Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA2 | Q9HCG7 | 18/20 | 0.50 |
| ▸ | GBA1 | P04062 | 7/20 | 0.50 |
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | UGCG | Q16739 | 3/20 | 0.50 |
| ▸ | MGAM | O43451 | 2/20 | 0.50 |
| ▸ | SI | P14410 | 2/20 | 0.50 |
| ▸ | AGL | P35573 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12325138 | 0.89 | GBA2 (0.57) | GBA2GBA1GAAUGCGMGAM | |
| SCHEMBL12289779 | 0.89 | GBA2 (0.57) | GBA2GBA1GAAUGCGMGAM | |
| SCHEMBL941202 | 0.89 | GBA2 (0.57) | GBA2GBA1GAAUGCGMGAM | |
| SCHEMBL12191646 | 0.75 | GAA (0.51) | GBA2GBA1GAAUGCGMGAM | |
| Piperidine SCHEMBL1859503 | 0.74 | GLB1 (0.73) | GBA2GBA1GAAUGCGMGAM | |
| SCHEMBL12289778 | 0.72 | GAA (0.55) | GBA2GBA1GAAUGCGMGAM | |
| SCHEMBL941922 | 0.72 | GAA (0.55) | GBA2GBA1GAAUGCGMGAM | |
| SCHEMBL12325136 | 0.72 | GAA (0.55) | GBA2GBA1GAAUGCGMGAM | |
| SCHEMBL17795748 | 0.72 | GAA (0.55) | GBA2GBA1GAAUGCGMGAM | |
| SCHEMBL12909425 | 0.71 | GBA2 (0.54) | GBA2GBA1GAAUGCGMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010049678-A2 | TREATMENT OF ENERGY UTILIZATION DISEASES | SUMMIT CORPORATION PLC (GB) | 2010-05-06 | — | — | WO | disclosed |