Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | GRM8 | O00222 | 1/20 | 0.32 |
| ▸ | GRM6 | O15303 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381970 | 1.00 | KMT2A (0.50) | KMT2APMP22ALOX15BLMGRM8 | |
| SCHEMBL3382371 | 0.83 | KMT2A (0.47) | KMT2APMP22ALOX15BLMGRM8 | |
| SCHEMBL3382374 | 0.83 | KMT2A (0.47) | KMT2APMP22ALOX15BLMGRM8 | |
| SCHEMBL3382016 | 0.82 | TET2 (0.46) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL3382012 | 0.82 | TET2 (0.46) | GRM8GRM6GRIN2DGRIN3BGSR | |
| SCHEMBL11320655 | 0.80 | KMT2A (0.52) | KMT2APMP22ALOX15BLMGRM8 | |
| SCHEMBL5324406 | 0.80 | KMT2A (0.52) | KMT2APMP22ALOX15BLMGRM8 | |
| SCHEMBL5324410 | 0.80 | KMT2A (0.52) | KMT2APMP22ALOX15BLMGRM8 | |
| SCHEMBL11320661 | 0.80 | KMT2A (0.52) | KMT2APMP22ALOX15BLMGRM8 | |
| SCHEMBL23037168 | 0.78 | KMT2A (0.50) | KMT2APMP22ALOX15BLMGRM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | claimed |
| WO-2010017405-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF PAIN | HELLER ADAM (US) | 2010-02-11 | — | — | WO | disclosed |