⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphonic Acid SCHEMBL458503 | 0.72 | — | — | |
| Phosphonic Acid SCHEMBL29666079 | 0.72 | — | — | |
| Phosphonic Acid SCHEMBL3694758 | 0.72 | — | — | |
| Phosphonic Acid SCHEMBL3226571 | 0.72 | — | — | |
| Phosphonic Acid SCHEMBL4074 | 0.72 | — | — | |
| Phosphonic Acid SCHEMBL27583577 | 0.72 | — | — | |
| SCHEMBL8801933 | 0.72 | — | — | |
| Phosphonic Acid SCHEMBL10858975 | 0.71 | — | — | |
| Phosphonic Acid SCHEMBL23926539 | 0.67 | — | — | |
| Phosphonic Acid SCHEMBL8335746 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184703-A | Synthesis method of alpha-substituted chiral phosphonate compound | 中国人民解放军军事科学院防化研究院 | 2024-06-14 | — | — | CN | disclosed |
| EP-2945957-B1 | NOVEL WATER-SOLUBLE COMPLEXING AGENTS AND CORRESPONDING LANTHANIDE COMPLEXES | CISBIO BIOASSAYS (FR) | 2023-11-08 | — | — | EP | disclosed |
| WO-2021035037-A1 | METHOD TO INCREASE SYSTEMIC BLOOD PRESSURE IN SHOCK | GEORGETOWN UNIVERSITY (US) | 2021-02-25 | — | — | WO | disclosed |
| US-20150157584-A1 | INHIBITORS OF HIPPO-YAP SIGNALING PATHWAY | THE J. DAVID GLADSTONE INSTITUTES (US) | 2015-06-11 | — | — | US | disclosed |
| EP-2858635-A1 | INHIBITORS OF HIPPO-YAP SIGNALING PATHWAY | The Regents of The University of California (US) | 2015-04-15 | — | — | EP | disclosed |
| WO-2013188138-A1 | INHIBITORS OF HIPPO-YAP SIGNALING PATHWAY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-12-19 | — | — | WO | disclosed |
| US-8445706-B2 | Unnatural amino acids capable of covalently modifying protein phosphatases and their use as general and specific inhibitors and probes | BOARD OF TRUSTEES OF NORTHERN ILLINOIS UNIVERSITY (US) | 2013-05-21 | — | — | US | disclosed |
| US-20100061936-A1 | UNNATURAL AMINO ACIDS CAPABLE OF COVALENTLY MODIFYING PROTEIN PHOSPHATASES AND THEIR USE AS GENERAL AND SPECIFIC INHIBITORS AND PROBES | BOARD OF TRUSTEES OF NORTHERN ILLINOIS UNIVERSITY | 2010-03-11 | — | — | US | disclosed |