Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3383984 | 0.89 | KDR (0.68) | KDRFGFR3 | |
| SCHEMBL3385522 | 0.89 | FGFR3 (0.61) | KDRFGFR3 | |
| SCHEMBL3380727 | 0.87 | KDR (0.70) | KDRFGFR3 | |
| SCHEMBL3382054 | 0.86 | KDR (0.55) | KDRFGFR3 | |
| SCHEMBL3383579 | 0.86 | FGFR3 (0.59) | KDRFGFR3 | |
| SCHEMBL3184677 | 0.86 | FGFR3 (0.57) | KDRFGFR3 | |
| SCHEMBL3177632 | 0.86 | FGFR3 (0.56) | KDRFGFR3 | |
| SCHEMBL27705887 | 0.86 | FGFR3 (0.54) | KDRFGFR3 | |
| SCHEMBL3196184 | 0.86 | KDR (0.58) | KDRFGFR3 | |
| SCHEMBL3185744 | 0.85 | KDR (0.57) | KDRFGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904494-B1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS | LILLY CO ELI (US) | 2010-12-01 | — | — | EP | disclosed |