Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 11/20 | 0.57 |
| ▸ | FLT3 | P36888 | 9/20 | 0.53 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3384216 | 0.86 | KDR (0.53) | KDRFLT3FGFR3 | |
| SCHEMBL17556214 | 0.83 | KDR (0.82) | KDRFLT3FGFR3 | |
| SCHEMBL3027930 | 0.81 | KDR (0.60) | KDRFLT3FGFR3 | |
| SCHEMBL3186080 | 0.80 | KDR (0.74) | KDRFLT3FGFR3 | |
| SCHEMBL3196127 | 0.79 | KDR (0.71) | KDRFLT3FGFR3 | |
| SCHEMBL3381974 | 0.78 | KDR (0.49) | KDRFLT3FGFR3 | |
| SCHEMBL20399834 | 0.76 | KDR (0.57) | KDRFLT3FGFR3 | |
| SCHEMBL3188804 | 0.76 | KDR (0.45) | KDRFLT3FGFR3 | |
| SCHEMBL25261576 | 0.75 | FLT3 (0.71) | KDRFLT3 | |
| SCHEMBL3382949 | 0.75 | FLT3 (0.58) | KDRFLT3FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904494-B1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS | LILLY CO ELI (US) | 2010-12-01 | — | — | EP | disclosed |