Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7863760 | 0.94 | MAPT (0.72) | ATMMAPTTDP1PABPC1ALOX15 | |
| SCHEMBL3230209 | 0.91 | ATM (0.69) | ATMMAPTTDP1PABPC1ALOX15 | |
| SCHEMBL3235845 | 0.89 | ATM (0.66) | ATMMAPTTDP1PABPC1ALOX15 | |
| SCHEMBL3384743 | 0.89 | MAPT (0.67) | ATMMAPTTDP1PABPC1ALOX15 | |
| SCHEMBL3605297 | 0.88 | ATM (0.65) | ATMMAPTTDP1PABPC1ALOX15 | |
| SCHEMBL3385026 | 0.88 | ATM (0.65) | ATMMAPTTDP1PABPC1ALOX15 | |
| SCHEMBL3384994 | 0.87 | MAPT (0.68) | ATMMAPTTDP1PABPC1ALOX15 | |
| SCHEMBL3384789 | 0.87 | ATM (0.64) | ATMMAPTTDP1PABPC1ALOX15 | |
| SCHEMBL3615253 | 0.86 | ATM (0.69) | ATMMAPTTDP1PABPC1ALOX15 | |
| SCHEMBL14334424 | 0.86 | ATM (0.62) | ATMMAPTTDP1PABPC1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149551-A1 | N-(indol-3-ylalkyl)-(hetero)arylamid derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | claimed |
| EP-2149551-A1 | N-(indol-3-ylalkyl)-(hetero)arylamid derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | disclosed |