Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6261430 | 0.98 | KCNH2 (0.52) | KCNH2NPC1KDM4EMAPTHSD17B10 | |
| SCHEMBL7191737 | 0.89 | KCNH2 (0.47) | KCNH2NPC1KDM4EMAPTHSD17B10 | |
| SCHEMBL5175466 | 0.86 | KCNH2 (0.45) | KCNH2NPC1KDM4EMAPTHSD17B10 | |
| SCHEMBL6870781 | 0.84 | KCNH2 (0.48) | KCNH2NPC1KDM4EMAPTHSD17B10 | |
| SCHEMBL16600073 | 0.83 | KCNH2 (0.55) | KCNH2NPC1KDM4EMAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL6864676 | 0.82 | KCNH2 (0.47) | KCNH2NPC1KDM4EMAPTHSD17B10 | |
| SCHEMBL8234801 | 0.82 | KCNH2 (0.72) | KCNH2HDAC1HDAC2HDAC3 | |
| SCHEMBL3530209 | 0.81 | NPC1 (0.46) | KCNH2NPC1KDM4EMAPTHSD17B10 | |
| SCHEMBL6137070 | 0.81 | KDM4E (0.46) | KCNH2NPC1KDM4EMAPTHSD17B10 | |
| SCHEMBL21052177 | 0.81 | KCNH2 (0.50) | KCNH2NPC1KDM4EMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2652 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113912804-B | Construction method and application of electrochemical luminescence system based on extrapolation receptor type covalent organic framework | 南昌大学 | 2023-03-14 | — | — | CN | claimed |
| US-11555017-B2 | Oxidation base derived from 1-hexyl-4,5-diaminopyrazole, composition containing same and use thereof in oxidation dyeing of keratin fibres | L'OREAL (FR) | 2023-01-17 | — | — | US | claimed |
| CN-113912804-A | Construction method and application of electrochemical luminescence system based on extrapolation receptor type covalent organic framework | 南昌大学 | 2022-01-11 | — | — | CN | claimed |
| US-20200392088-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2020-12-17 | — | — | US | claimed |
| EP-3638200-A1 | PROCESS FOR DYEING KERATIN MATERIALS USING AT LEAST ONE BLUE, PURPLE OR GREEN DYE AND AT LEAST ONE DISULFIDE, THIOL OR PROTECTED THIOL FLUORESCENT DYE | L'Oreal (FR) | 2020-04-22 | — | — | EP | claimed |
| EP-3464247-B1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | OREAL (FR) | 2020-03-11 | — | — | EP | claimed |
| EP-3464247-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | L'Oréal (FR) | 2019-04-10 | — | — | EP | claimed |
| WO-2018229296-A1 | PROCESS FOR DYEING KERATIN MATERIALS USING AT LEAST ONE BLUE, PURPLE OR GREEN DYE AND AT LEAST ONE DISULFIDE, THIOL OR PROTECTED THIOL FLUORESCENT DYE | L'OREAL (FR) | 2018-12-20 | — | — | WO | claimed |
| WO-2017202884-A1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | L'OREAL (FR) | 2017-11-30 | — | — | WO | claimed |
| CN-101444460-B | Oxidation dye composition, oxidation dyeing process and use | OU LAIYA | 2013-08-14 | — | — | CN | claimed |
| US-20030093867-A1 | Dyes for keratin fibres containing 1,3-diamino-4-heteroarylbenzene derivatives and novel 1,3-diamino-4-heteroarylbenzene derivatives | HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) | 2003-05-22 | — | — | US | claimed |
| US-6503282-B1 | Composition for coloring keratin fibers based on a developer-coupler combination characterized in that it contains as the coupler 3-(2,4-diaminophenoxy)-1-propanol and as the developer ring and having general formula (I) | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-07 | — | — | US | claimed |
| US-6409773-B1 | AMINOPHENOL COUPLERS | CLAIROL INCORPORATED | 2002-06-25 | — | — | US | claimed |
| WO-2002047635-A1 | NOVEL COUPLER FOR USE IN OXIDATIVE HAIR DYEING | P&G-CLAIROL, INC. (US) | 2002-06-20 | — | — | WO | claimed |
| EP-1166749-A2 | Composition and process for dyeing keratinic fibres | Wella Aktiengesellschaft (DE) | 2002-01-02 | — | — | EP | claimed |
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | claimed |
| EP-1158954-A1 | MEANS AND METHOD FOR DYING KERATINIC FIBRES | Wella Aktiengesellschaft (DE) | 2001-12-05 | — | — | EP | claimed |
| WO-2001051019-A1 | MEANS AND METHOD FOR DYING KERATINIC FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2001-07-19 | — | — | WO | claimed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | claimed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | claimed |