Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM2 | Q9P1W9 | 16/20 | 0.62 |
| ▸ | PIM1 | P11309 | 14/20 | 0.62 |
| ▸ | PIM3 | Q86V86 | 13/20 | 0.62 |
| ▸ | STK17B | O94768 | 2/20 | 0.53 |
| ▸ | BCL2 | P10415 | 2/20 | 0.53 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.53 |
| ▸ | CDK7 | P50613 | 2/20 | 0.53 |
| ▸ | DAPK1 | P53355 | 2/20 | 0.53 |
| ▸ | CAMK4 | Q16566 | 2/20 | 0.53 |
| ▸ | MAPK15 | Q8TD08 | 2/20 | 0.53 |
| ▸ | PNPLA2 | Q96AD5 | 2/20 | 0.53 |
| ▸ | HIPK3 | Q9H422 | 2/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1580451 | 1.00 | PIM2 (0.62) | PIM2PIM1PIM3STK17BBCL2 | |
| Trifluoroacetic Acid SCHEMBL1580447 | 1.00 | PIM2 (0.62) | PIM2PIM1PIM3STK17BBCL2 | |
| SCHEMBL1580435 | 0.95 | PIM2 (0.68) | PIM2PIM1PIM3STK17BBCL2 | |
| SCHEMBL12281916 | 0.95 | PIM2 (0.68) | PIM2PIM1PIM3STK17BBCL2 | |
| SCHEMBL2425076 | 0.95 | PIM2 (0.68) | PIM2PIM1PIM3STK17BBCL2 | |
| SCHEMBL12282168 | 0.95 | PIM2 (0.68) | PIM2PIM1PIM3STK17BBCL2 | |
| SCHEMBL2425080 | 0.95 | PIM2 (0.68) | PIM2PIM1PIM3STK17BBCL2 | |
| SCHEMBL1580433 | 0.95 | PIM2 (0.68) | PIM2PIM1PIM3STK17BBCL2 | |
| SCHEMBL1580455 | 0.89 | PIM2 (0.67) | PIM2PIM1PIM3STK17BBCL2 | |
| SCHEMBL1580457 | 0.89 | PIM2 (0.67) | PIM2PIM1PIM3STK17BBCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001169-A2 | CHEMICAL COMPOUNDS 251 | ASTRAZENECA AB (SE) | 2010-01-07 | — | — | WO | disclosed |