⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27769296 | 0.81 | — | — | |
| SCHEMBL183475 | 0.81 | — | — | |
| SCHEMBL7075554 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL11782854 | 0.79 | KMT2A (0.50) | — | |
| SCHEMBL279818 | 0.79 | — | — | |
| SCHEMBL6853502 | 0.77 | KMT2A (0.38) | — | |
| SCHEMBL14372978 | 0.76 | MAPT (0.56) | — | |
| SCHEMBL11195256 | 0.76 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL18463708 | 0.76 | S1PR4 (0.37) | — | |
| SCHEMBL9373295 | 0.76 | KDM4E (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106905146-B | Method for selective catalytic oxidation of biomass-based furan compound | 华南理工大学 | 2020-02-18 | — | — | CN | claimed |
| CN-106905146-A | A kind of method of biomass-based furan compound selective catalytic oxidation | 华南理工大学 | 2017-06-30 | — | — | CN | claimed |
| CN-115894407-A | CIT fluorophore of 1-furan and thienyl-2-alkenyl-1-ketone containing nitrogen mustard and preparation method and application thereof | 广东海洋大学 | 2023-04-04 | — | — | CN | disclosed |
| CN-106905146-B | Method for selective catalytic oxidation of biomass-based furan compound | 华南理工大学 | 2020-02-18 | — | — | CN | disclosed |
| US-8937091-B2 | Inhibitor of protein crosslinking and use of the same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2015-01-20 | — | — | US | disclosed |
| EP-2027124-B1 | IMIDAZOLOPYRAZINE COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES | JANSSEN PHARMACEUTICA NV (BE) | 2013-07-03 | — | — | EP | disclosed |
| US-20120277423-A1 | PROTEIN CROSSLINKING INHIBITOR AND USE OF THE SAME | JAPAN SCIENCE AND TECHNOLOGY AGENCY | 2012-11-01 | — | — | US | disclosed |
| EP-1748986-B1 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS ALDOSTERONE SYNTHASE INHIBITORS | NOVARTIS AG (CH) | 2010-12-01 | — | — | EP | disclosed |
| US-7432058-B2 | Methods of labeling nucleic acids with energy transfer dyes | APPLERA CORPORATION (US) | 2008-10-07 | — | — | US | disclosed |
| US-20080076794-A1 | Hyperaldosteronism | NOVARTIS AG (CH) | 2008-03-27 | — | — | US | disclosed |
| US-20070212709-A1 | Non-nucleosidic linker linking xanthene donor to 4,7-dichlororhodamine acceptor; | APPLERA CORPORATION (US) | 2007-09-13 | — | — | US | disclosed |
| WO-2005118541-A2 | HETEROCYCLIC COMPOUNDS AND THEIR USE AS ALDOSTERONE SYNTHASE INHIBITORS | SPEEDEL EXPERIMENTA AG (CH) | 2005-12-15 | — | — | WO | disclosed |
| US-6831177-B1 | Preparation of their intermediates, 2-acyl-5-benzylfuran derivatives and 1,2,4-triazole-3- carboxylic acid ester derivatives | SHIONOGI & CO., LTD. (JP) | 2004-12-14 | — | — | US | disclosed |
| EP-0974602-B1 | Catalyst and process for hydrogenating olefinically unsaturated compound | JSR CORP (JP) | 2004-01-02 | — | — | EP | disclosed |
| CN-1367784-A | Process for preparing substituted propenone derivatives | SHIONOGI & CO (JP) | 2002-09-04 | — | — | CN | disclosed |
| US-20020091148-A1 | 3-substituted indole antiproliferative angiogenesis inhibitors | ABBOTT LABORATORIES | 2002-07-11 | — | — | US | disclosed |
| WO-2002022576-A2 | 3-SUBSTITUTED INDOLE CARBOHYDRAZIDES USEFUL AS CELL PROLIFERATION AND ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2002-03-21 | — | — | WO | disclosed |
| EP-1186599-A1 | NOVEL PROCESSES FOR THE PREPARATION OF SUBSTITUTED PROPENONE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |
| US-6291596-B1 | CONTACTING OLEFINICALLY UNSATURATED COMPOUND WITH HYDROGEN IN THE PRESENCE OF A HYDROGENATION CATALYST COMPRISING TITANIUM OR ZIRCONIUM OR HAFNIUM COMPOUND IN AN INERT, ORGANIC SOLVENT | JSR CORPORATION (JP) | 2001-09-18 | — | — | US | disclosed |
| EP-0974602-A1 | Catalyst and process for hydrogenating olefinically unsaturated compound | JSR Corporation (JP) | 2000-01-26 | — | — | EP | disclosed |