Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL3387183

O=C(O)CO.OCCOCCO

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.62
MAPK1 P28482 1/20 0.62
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
ALDH1A1 P00352 1/20 0.43
BLM P54132 1/20 0.39
PMP22 Q01453 1/20 0.39
HSD17B10 Q99714 1/20 0.39
THRB P10828 1/20 0.39
HTT P42858 1/20 0.39
MAPT P10636 1/20 0.39
CAMK2A Q9UQM7 1/20 0.36
OR51E2 Q9H255 1/20 0.33
GPR84 Q9NQS5 1/20 0.33
FFAR1 O14842 1/20 0.33
FFAR4 Q5NUL3 1/20 0.33
LDHA P00338 1/20 0.32
SRR Q9GZT4 1/20 0.32
LMNA P02545 1/20 0.32
ALKBH5 Q6P6C2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Di(Hydroxyethyl)Ether SCHEMBL3385886 1.00 TSHR (0.62) TSHRMAPK1MEN1KMT2AALDH1A1
Glycolic Acid SCHEMBL20913722 0.97 MEN1 (0.65) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL9273841 0.87 TSHR (0.71) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL11094800 0.87 TSHR (0.71) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL2512495 0.87 TSHR (0.71) TSHRMAPK1MEN1KMT2AALDH1A1
Succinic Acid SCHEMBL1986734 0.85 TSHR (0.59) TSHRMAPK1MEN1KMT2AALDH1A1
Malonic Acid SCHEMBL8290814 0.85 TSHR (0.59) TSHRMAPK1MEN1KMT2AALDH1A1
Malonic Acid SCHEMBL31212384 0.85 TSHR (0.59) TSHRMAPK1MEN1KMT2AALDH1A1
Pentaethylene Glycol SCHEMBL9467222 0.84 KMT2A (0.73) TSHRMAPK1MEN1KMT2AALDH1A1
Hexaethylene Glycol SCHEMBL9467416 0.84 KMT2A (0.73) TSHRMAPK1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118541342-A Method of 庄信万丰股份有限公司 2024-08-23 CN claimed
WO-2023156764-A1 PROCESS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2023-08-24 WO claimed
EP-1756353-B1 ACID DONORS FOR DYEING POLYAMIDE HUNTSMAN ADV MAT SWITZERLAND (CH) 2010-12-01 EP claimed
US-7728067-B2 Acid donors for dyeing polyamide HUNTSMAN INTERNATIONAL LLC (US) 2010-06-01 US claimed
US-20080271260-A1 Acid Donors for Dyeing Polyamide PETER HANS-JORG 2008-11-06 US claimed
EP-1756353-A1 ACID DONORS FOR DYEING POLYAMIDE Huntsman Advanced Materials (Switzerland) GmbH (CH) 2007-02-28 EP claimed
WO-2005106107-A1 ACID DONORS FOR DYEING POLYAMIDE HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2005-11-10 WO claimed
US-4283581-A HYDROGENATION CATALYST OF SILICA AND COPPER OR A COPPER COMPOUND AND ZINC OXIDE CHEVRON RESEARCH COMPANY (US) 1981-08-11 US claimed
US-4149021-A Ester hydrogenation using cobalt, zinc and copper oxide catalyst CHEVRON RESEARCH COMPANY (US) 1979-04-10 US claimed
US-4087470-A CYCLIC, FROM FORMALDEHYDE AND SYNTHESIS GAS WITH HYDROGEN FLUORIDE CATALYST CHEVRON RESEARCH COMPANY (US) 1978-05-02 US claimed
CN-118541342-A Method of 庄信万丰股份有限公司 2024-08-23 CN disclosed
WO-2023156764-A1 PROCESS JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2023-08-24 WO disclosed
EP-1756353-B1 ACID DONORS FOR DYEING POLYAMIDE HUNTSMAN ADV MAT SWITZERLAND (CH) 2010-12-01 EP disclosed
US-7728067-B2 Acid donors for dyeing polyamide HUNTSMAN INTERNATIONAL LLC (US) 2010-06-01 US disclosed
US-20080271260-A1 Acid Donors for Dyeing Polyamide PETER HANS-JORG 2008-11-06 US disclosed
US-4199479-A Hydrogenation catalyst CHEVRON RESEARCH COMPANY (US) 1980-04-22 US disclosed
US-4149021-A Ester hydrogenation using cobalt, zinc and copper oxide catalyst CHEVRON RESEARCH COMPANY (US) 1979-04-10 US disclosed
US-4113662-A COBALT, ZINC AND COPPER CHEVRON RESEARCH COMPANY (US) 1978-09-12 US disclosed
US-4087470-A CYCLIC, FROM FORMALDEHYDE AND SYNTHESIS GAS WITH HYDROGEN FLUORIDE CATALYST CHEVRON RESEARCH COMPANY (US) 1978-05-02 US disclosed
US-4087470-A CYCLIC, FROM FORMALDEHYDE AND SYNTHESIS GAS WITH HYDROGEN FLUORIDE CATALYST CHEVRON RESEARCH COMPANY (US) 1978-05-02 US disclosed