Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | ACACA | Q13085 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3385920 | 0.89 | SLC1A3 (0.30) | — | |
| SCHEMBL3383772 | 0.88 | PIK3CD (0.34) | IRAK4ACACB | |
| SCHEMBL21429865 | 0.84 | IRAK4 (0.35) | AOC3IRAK4MCHR1ACACBACACA | |
| SCHEMBL12689563 | 0.84 | IRAK4 (0.35) | AOC3IRAK4MCHR1ACACBACACA | |
| SCHEMBL26456430 | 0.81 | MCHR1 (0.35) | AOC3IRAK4MCHR1 | |
| SCHEMBL18787795 | 0.79 | AOC3 (0.37) | AOC3IRAK4ACACBACACAGRM5 | |
| SCHEMBL18787635 | 0.79 | AOC3 (0.37) | AOC3IRAK4ACACBACACAGRM5 | |
| SCHEMBL18787634 | 0.79 | AOC3 (0.37) | AOC3IRAK4ACACBACACAGRM5 | |
| SCHEMBL19812708 | 0.79 | AOC3 (0.37) | AOC3IRAK4ACACBACACAGRM5 | |
| SCHEMBL10958265 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018132-A1 | COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-02-18 | — | — | WO | disclosed |