SCHEMBL33882

SCHEMBL33882

Cn1nc(N)c(NCCO)c1N

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 2/20 0.38
HRH4 Q9H3N8 2/20 0.33
CCNT1 O60563 1/20 0.33
CDK4 P11802 1/20 0.33
CCNB1 P14635 1/20 0.33
CCND1 P24385 1/20 0.33
CCNE1 P24864 1/20 0.33
CDK2 P24941 1/20 0.33
CDK9 P50750 1/20 0.33
GAA P10253 3/20 0.33
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MITF O75030 1/20 0.33
LMNA P02545 1/20 0.33
TTR P02766 1/20 0.33
GLA P06280 1/20 0.33
POLB P06746 1/20 0.33
RAD52 P43351 1/20 0.33
RAB9A P51151 1/20 0.33
MAPK1 P28482 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20136162 0.93 CDK1 (0.35) CDK1HRH4
Sulfuric Acid SCHEMBL7777786 0.92 CDK1 (0.34) CDK1HRH4ALDH1A1LMNAPOLB
SCHEMBL8025225 0.74 CDK1 (0.38) CDK1HRH4GAAALDH1A1POLB
SCHEMBL34103 0.71 CCNT1 (0.38) CDK1CCNT1CDK4CCNB1CCND1
SCHEMBL14321629 0.68 CCNT1 (0.33) CDK1CCNT1CDK4CCNB1CCND1
SCHEMBL1701046 0.68 CCNT1 (0.33) CDK1CCNT1CDK4CCNB1CCND1
Sulfuric Acid SCHEMBL7778359 0.67 CCNT1 (0.33) CDK1CCNT1CDK4CCNB1CCND1
SCHEMBL6275308 0.67 MAPK1 (0.34) GAAALDH1A1KDM4EMITFLMNA
SCHEMBL28271664 0.67 CDK1 (0.38) CDK1HRH4GAAALDH1A1KDM4E
SCHEMBL1801275 0.66 KDM4E (0.35) CDK1HRH4CDK9GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2395 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11555017-B2 Oxidation base derived from 1-hexyl-4,5-diaminopyrazole, composition containing same and use thereof in oxidation dyeing of keratin fibres L'OREAL (FR) 2023-01-17 US claimed
US-20200392088-A1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES L'OREAL (FR) 2020-12-17 US claimed
EP-3142638-B1 COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER OREAL (FR) 2020-08-12 EP claimed
EP-3464247-B1 NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES OREAL (FR) 2020-03-11 EP claimed
US-9993409-B2 Composition for dyeing keratin fibres, comprising an oxidation base and a particular heteroaryl coupler L'OREAL (FR) 2018-06-12 US claimed
US-20170087075-A1 COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING AN OXIDATION BASE AND A PARTICULAR HETEROARYL COUPLER L'OREAL (FR) 2017-03-30 US claimed
EP-1345580-B9 COMPOSITION FOR OXIDATION DYEING OF KERATINOUS FIBRES COMPRISING A DIAMINO PYRAZOLE AND A CARBONYL COMPOUND OREAL (FR) 2009-11-25 EP claimed
EP-1413286-B1 Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent OREAL (FR) 2009-04-22 EP claimed
US-7413579-B2 Method for dyeing fibers containing keratin HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-08-19 US claimed
EP-1405627-B1 Antipenetrating hair pretreatment composition based on polyethelenoxide polymer(s) and process using said composition for limiting skin penetration by colourants OREAL (FR) 2008-04-30 EP claimed
US-6306181-B1 FOR DYEING HUMAN HAIR L'OREAL (FR) 2001-10-23 US claimed
EP-0786244-B1 Oxidation hair-dye comprising 3,4,5 triaminopyrazole derivatives, and novel 3,4,5 triaminopyrazole derivatives WELLA AG (DE) 2001-09-19 EP claimed
US-6241784-B1 COSMETICS OR SKIN COMPOSITION FOR TREATING FIBERS L'OREAL S.A. (FR) 2001-06-05 US claimed
US-6228129-B1 OXIDATION BASE, CATIONIC DIRECT DYE AND AN ENZYME OF 2-ELECTRON OXIDOREDUCTASES IN THE PRESENCE OF A DONOR FOR THE ENZYME L'OREAL S.A. (FR) 2001-05-08 US claimed
EP-1093788-A1 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP claimed
EP-1068860-A1 Dyeing composition containing 1-acetoxy naphthalene, two oxidation bases and a coupling agent L'OREAL (FR) 2001-01-17 EP claimed
EP-1011619-A1 DYEING COMPOSITION FOR KERATIN FIBRES L'OREAL (FR) 2000-06-28 EP claimed
WO-1999011231-A1 DYEING COMPOSITION FOR KERATIN FIBRES L'OREAL (FR) 1999-03-11 WO claimed
US-5766576-A NONTOXIC DYE DEVELOPER; WASHFASTNESS, COLORFASTNESS, RED COLOR INTENSITY WELLA AKTIENGESELLSCHAFT (DE) 1998-06-16 US claimed
EP-0786244-A1 Oxidation hair-dye comprising 3,4,5 triaminopyrazole derivatives, and novel 3,4,5 triaminopyrazole derivatives Wella Aktiengesellschaft (DE) 1997-07-30 EP claimed