Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 16/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.51 |
| ▸ | FPR3 | P25089 | 1/20 | 0.50 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358218 | 0.89 | CCR1 (0.51) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL3358210 | 0.89 | CCR1 (0.51) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL3355002 | 0.82 | CCR1 (0.54) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL3355449 | 0.82 | CCR1 (0.54) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL3353758 | 0.78 | CCR1 (0.53) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL3353757 | 0.78 | CCR1 (0.53) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL3355615 | 0.76 | CCR1 (0.49) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL3355628 | 0.76 | CCR1 (0.49) | CCR1PTGDR2FPR3GPR65GPR35 | |
| Chlorobenzene SCHEMBL27693442 | 0.73 | CCR1 (0.66) | CCR1PTGDR2FPR3GPR65GPR35 | |
| SCHEMBL3354632 | 0.73 | CCR1 (0.53) | CCR1PTGDR2FPR3GPR65GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068881-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-06-17 | — | — | WO | disclosed |