Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13763147 | 0.90 | PDE5A (0.69) | PDE5AKCNH2 | |
| SCHEMBL332289 | 0.88 | PDE5A (0.78) | PDE5AKCNH2 | |
| SCHEMBL332278 | 0.87 | PDE5A (0.89) | PDE5AKCNH2 | |
| SCHEMBL4701111 | 0.86 | PDE5A (0.68) | PDE5AKCNH2 | |
| Pf-00489791 SCHEMBL29379715 | 0.86 | PDE5A (1.00) | PDE5AKCNH2 | |
| Pf-00489791 SCHEMBL331279 | 0.86 | PDE5A (1.00) | PDE5AKCNH2 | |
| SCHEMBL4703074 | 0.85 | PDE5A (0.61) | PDE5AKCNH2 | |
| SCHEMBL4702131 | 0.85 | PDE5A (0.64) | PDE5AKCNH2 | |
| SCHEMBL4702163 | 0.85 | PDE5A (0.71) | PDE5AKCNH2 | |
| SCHEMBL331644 | 0.85 | PDE5A (0.85) | PDE5AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881985-B1 | ANHYDROUS CRYSTALLINE FORMS OF N-Ý1-(2-ETHOXYETHYL)-5-(N-ETHYL-N-METHYLAMINO)-7-(4-METHYLPYRIDIN-2-YL-AMINO)-1H-PYRAZOLO[4,3-D]PYRIMIDINE-3-CARBONYL¨METHANESULFONAMIDE | PFIZER (US) | 2010-12-29 | — | — | EP | claimed |