Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11835015 | 0.91 | BRD4 (0.36) | BRD4BRD2TSHRLMNAPIK3CD | |
| Methyl Alcohol SCHEMBL9485563 | 0.88 | BRD4 (0.43) | BRD4BRD2TSHRALDH1A1LMNA | |
| Acetic Acid SCHEMBL28084245 | 0.87 | BRD4 (0.36) | BRD4BRD2TSHRALDH1A1LMNA | |
| Acetic Acid SCHEMBL887070 | 0.87 | BRD4 (0.39) | BRD4BRD2TSHRALDH1A1LMNA | |
| Hydrogen Peroxide SCHEMBL2561887 | 0.86 | BRD4 (0.39) | BRD4BRD2TSHRALDH1A1LMNA | |
| Zinc Ion SCHEMBL28252562 | 0.86 | BRD4 (0.39) | BRD4BRD2TSHRLMNAPIK3CD | |
| Hydrogen Peroxide SCHEMBL610401 | 0.86 | BRD4 (0.39) | BRD4BRD2TSHRALDH1A1LMNA | |
| SCHEMBL10869 | 0.86 | — | — | |
| SCHEMBL5473091 | 0.86 | BRD4 (0.42) | BRD4BRD2TSHRALDH1A1LMNA | |
| SCHEMBL10476826 | 0.86 | BRD4 (0.35) | BRD4BRD2TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8211456-B2 | Method of modifying materials surfaces | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2012-07-03 | — | — | US | disclosed |
| EP-1945688-B1 | METHOD OF MODIFYING MATERIALS SURFACES | TNO (NL) | 2010-12-15 | — | — | EP | disclosed |
| US-20090280157-A1 | Method of Modifying Materials Surfaces | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2009-11-12 | — | — | US | disclosed |
| EP-1945688-A1 | METHOD OF MODIFYING MATERIALS SURFACES | Nederlandse Organisatie voor Toegepast-Natuuurwetenschappelijk Onderzoek TNO (NL) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007021180-A1 | METHOD OF MODIFYING MATERIALS SURFACES | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 2007-02-22 | — | — | WO | disclosed |
| EP-1754731-A1 | Method of modifying materials surfaces | Nederlandse Organisatie voor Toegepast-Natuuurwetenschappelijk Onderzoek TNO (NL) | 2007-02-21 | — | — | EP | disclosed |
| EP-0220660-B1 | SEMI-PERMEABLES MEMBRANES PREPARED VIA REACTION OF CATIONIC GROUPS WITH NUCLEOPHILIC GROUPS | THE DOW CHEMICAL COMPANY (US) | 1992-03-11 | — | — | EP | disclosed |
| US-4839203-A | COVALENT BONDING PRODUCING A COMPOSITE | THE DOW CHEMICAL COMPANY (US) | 1989-06-13 | — | — | US | disclosed |
| US-4797187-A | COACERVATION OF CATIONS | THE DOW CHEMICAL COMPANY (US) | 1989-01-10 | — | — | US | disclosed |
| US-4704324-A | REVERSE OSMOSIS, GAS SEPARATION, ULTRAFILTRATION | THE DOW CHEMICAL COMPANY (US) | 1987-11-03 | — | — | US | disclosed |
| WO-1987002682-A1 | SEMI-PERMEABLE MEMBRANES PREPARED VIA REACTION OF CATIONIC GROUPS WITH NUCLEOPHILIC GROUPS | THE DOW CHEMICAL COMPANY (US) | 1987-05-07 | — | — | WO | disclosed |
| EP-0220660-A2 | Semi-permeables membranes prepared via reaction of cationic groups with nucleophilic groups | THE DOW CHEMICAL COMPANY (US) | 1987-05-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090280157-A1 | Method of Modifying Materials Surfaces | EPCAM, CD44, MICA | BRD4 2408/4885BRD2 2187/4885TSHR 3688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.