SCHEMBL3389290

SCHEMBL3389290

CCC(CCN(CC)CC)N=C=N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL968431 0.98
Hydrochloric Acid SCHEMBL182034 0.80
Hydrochloric Acid SCHEMBL8472312 0.80
Iodomethane SCHEMBL8880489 0.78
SCHEMBL17599756 0.78
SCHEMBL28239800 0.76
SCHEMBL28480240 0.75
SCHEMBL9711018 0.74 CYP1A2 (0.33)
SCHEMBL15514440 0.72
SCHEMBL8669983 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8969543-B2 SiRNA-hydrophilic polymer conjugates for intracellular delivery of siRNA and method thereof BIONEER CORPORATION (KR) 2015-03-03 US claimed
US-20070287681-A1 siRNA-hydrophilic polymer conjugates for intracellular delivery of siRNA and method thereof BIONEER CORPORATION (KR) 2007-12-13 US claimed
EP-2152752-B1 ANTIBODY DIRECTED TO G PROTEIN COUPLED RECEPTORS (GPCR) HOFFMANN LA ROCHE (CH) 2017-11-08 EP disclosed
US-9789199-B2 MetAP-2 inhibitor polymersomes for therapeutic administration CHILDREN'S MEDICAL CENTER CORPORATION (US) 2017-10-17 US disclosed
US-9782489-B2 MetAP-2 inhibitor polymersomes for therapeutic administration CHILDREN'S MEDICAL CENTER CORPORATION (US) 2017-10-10 US disclosed
US-20160375144-A1 METAP-2 INHIBITOR POLYMERSOMES FOR THERAPEUTIC ADMINISTRATION CHILDREN'S MEDICAL CENTER CORPORATION (US) 2016-12-29 US disclosed
US-20160361428-A1 METAP-2 INHIBITOR POLYMERSOMES FOR THERAPEUTIC ADMINISTRATION CHILDREN'S MEDICAL CENTER CORPORATION (US) 2016-12-15 US disclosed
US-9446140-B2 MetAP-2 inhibitor polymersomes for therapeutic administration CHILDREN'S MEDICAL CENTER CORPORATION (US) 2016-09-20 US disclosed
US-20160136292-A1 METAP-2 INHIBITOR POLYMERSOMES FOR THERAPEUTIC ADMINISTRATION CHILDREN'S MEDICAL CENTER CORPORATION (US) 2016-05-19 US disclosed
EP-1915449-B1 SIRNA-HYDROPHILIC POLYMER CONJUGATES FOR INTRACELLULAR DELIVERY OF SIRNA AND METHOD THEREOF BIONEER CORP (KR) 2016-03-23 EP disclosed
US-9272050-B2 MetAP-2 inhibitor polymersomes for therapeutic administration CHILDREN'S MEDICAL CENTER CORPORATION (US) 2016-03-01 US disclosed
US-20100111894-A1 METAP-2 INHIBITOR POLYMERSOMES FOR THERAPEUTIC ADMINISTRATION CHILDREN'S MEDICAL CENTER CORPORATION (US) 2010-05-06 US disclosed
EP-2170402-A2 METAP-2 INHIBITOR POLYMERSOMES FOR THERAPEUTIC ADMINISTRATION CHILDREN'S MEDICAL CENTER CORPORATION (US) 2010-04-07 EP disclosed
WO-2009036108-A1 METHODS AND COMPOSITIONS FOR INHIBITING VASCULAR LEAKAGE CHILDREN'S MEDICAL CENTER CORPORATION (US) 2009-03-19 WO disclosed
WO-2009003110-A2 METAP-2 INHIBITOR POLYMERSOMES FOR THERAPEUTIC ADMINISTRATION CHILDREN'S MEDICAL CENTER CORPORATION (US) 2008-12-31 WO disclosed
US-20070287681-A1 siRNA-hydrophilic polymer conjugates for intracellular delivery of siRNA and method thereof BIONEER CORPORATION (KR) 2007-12-13 US disclosed
US-5304498-A Method and composition for free ligand assay EKINS ROGER PHILIP (GB) 1994-04-19 US disclosed
EP-0103605-B1 METHOD FOR FREE LIGAND ASSAYS EKINS, Roger Philip (GB) 1990-12-05 EP disclosed
EP-0103605-A1 METHOD FOR FREE LIGAND ASSAYS. EKINS ROGER PHILIP 1984-03-28 EP disclosed
WO-1983003306-A1 METHOD AND COMPOSITION FOR FREE LIGAND ASSAYS EKINS, ROGER, PHILIP 1983-09-29 WO disclosed