Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 16/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 13/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3390146 | 0.99 | HCRTR2 (0.53) | HCRTR2HCRTR1CYP3A4 | |
| SCHEMBL3383694 | 0.90 | HCRTR2 (0.50) | HCRTR2HCRTR1 | |
| Hydrochloric Acid SCHEMBL3388194 | 0.89 | HCRTR2 (0.49) | HCRTR2HCRTR1 | |
| SCHEMBL3387276 | 0.86 | HCRTR2 (0.63) | HCRTR2HCRTR1 | |
| Hydrochloric Acid SCHEMBL3383575 | 0.85 | HCRTR2 (0.62) | HCRTR2HCRTR1 | |
| SCHEMBL10121575 | 0.84 | HCRTR2 (0.53) | HCRTR2HCRTR1 | |
| SCHEMBL7911805 | 0.83 | HCRTR2 (0.53) | HCRTR2HCRTR1 | |
| SCHEMBL3386456 | 0.81 | HCRTR1 (0.60) | HCRTR2HCRTR1CYP3A4 | |
| SCHEMBL262832 | 0.81 | HCRTR1 (0.60) | HCRTR2HCRTR1CYP3A4 | |
| SCHEMBL3383668 | 0.80 | HCRTR2 (0.55) | HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144760-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-06-10 | — | — | US | disclosed |
| US-20100144760-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-06-10 | — | — | US | disclosed |
| US-20100144760-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144760-A1 | NOVEL COMPOUNDS | HTR3B, HTR1B, HTR2B | HCRTR2 1425/4885HCRTR1 2016/4885CYP3A4 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.