Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 5/20 | 0.34 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | GPR3 | P46089 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.31 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzothiophene SCHEMBL29415494 | 0.86 | — | — | |
| Benzothiophene SCHEMBL253491 | 0.86 | CA12 (0.42) | CA12CA9CYP2A6CTNNB1WNT3A | |
| Benzothiophene SCHEMBL28545602 | 0.86 | CA12 (0.42) | CA12CA9CYP2A6CTNNB1WNT3A | |
| Benzothiophene SCHEMBL451494 | 0.86 | — | — | |
| Benzothiophene SCHEMBL7023 | 0.86 | — | — | |
| Benzothiophene SCHEMBL27873783 | 0.86 | CA12 (0.42) | CA12CA9CYP2A6CTNNB1WNT3A | |
| Benzothiophene SCHEMBL29383883 | 0.86 | — | — | |
| Benzothiophene SCHEMBL28399890 | 0.86 | CA12 (0.42) | CA12CA9CYP2A6CTNNB1WNT3A | |
| Naphthalene SCHEMBL23236453 | 0.84 | CYP2A6 (0.44) | CA12CA9CYP2A6CTNNB1WNT3A | |
| Benzothiophene SCHEMBL2495738 | 0.84 | CA12 (0.41) | CA12CA9CYP2A6CTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152241-A1 | INHIBITORS OF STORE OPERATED CALCIUM RELEASE | CALCIMEDICA, INC. (US) | 2010-06-17 | — | — | US | claimed |
| CN-115685684-A | Photosensitive composition, photosensitive composition layer, transfer film, and method for producing laminate having conductor pattern | 富士胶片株式会社 | 2023-02-03 | — | — | CN | disclosed |
| US-8524763-B2 | Inhibitors of store operated calcium release | CALCIMEDICA, INC. (US) | 2013-09-03 | — | — | US | disclosed |
| US-20100152241-A1 | INHIBITORS OF STORE OPERATED CALCIUM RELEASE | CALCIMEDICA, INC. (US) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152241-A1 | INHIBITORS OF STORE OPERATED CALCIUM RELEASE | ORAI1, SARAF, RYR2 | MAPK1 3448/4885TDP1 2319/4885CA12 4207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.