SCHEMBL339029

SCHEMBL339029

C=CCCO[SiH](CC)CC

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
ALDH1A1 P00352 1/20 0.36
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6064015 0.86 TSHR (0.44) TSHRALDH1A1
SCHEMBL6063938 0.84 TSHR (0.44) TSHRALDH1A1
SCHEMBL15302046 0.82 TSHR (0.48) TSHRALDH1A1
SCHEMBL6063339 0.81 TSHR (0.42) TSHRALDH1A1CA2CA9
SCHEMBL6062839 0.78 TSHR (0.46) TSHRALDH1A1
SCHEMBL340550 0.74
SCHEMBL339815 0.74
SCHEMBL7640822 0.73 TSHR (0.38) TSHRALDH1A1CA2CA9
SCHEMBL8436585 0.73 TSHR (0.43) TSHRALDH1A1CA2CA9
SCHEMBL673886 0.70 TSHR (0.33) TSHRALDH1A1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106800655-A A kind of organic silicon rigidity-increasing stick and preparation method thereof and a kind of silica-gel composition 比亚迪股份有限公司 2017-06-06 CN claimed
CN-105492539-B Curable organosilicon composition, its cured product and optical semiconductor device 美国陶氏有机硅公司 2019-05-07 CN disclosed
US-9994681-B2 Organopolysiloxane prepolymer and a curable organopolysiloxane composition comprising the same HENKEL AG & CO. KGAA (DE) 2018-06-12 US disclosed
EP-3245256-A1 ORGANOPOLYSILOXANE PREPOLYMER AND CURABLE ORGANOPOLYSILOXANE COMPOSITION COMPRISING SAME Henkel AG & Co. KGaA (DE) 2017-11-22 EP disclosed
US-20170306100-A1 Organopolysiloxane Prepolymer and a Curable Organopolysiloxane Composition Comprising the Same HENKEL CORPORATION 2017-10-26 US disclosed
CN-106800655-A A kind of organic silicon rigidity-increasing stick and preparation method thereof and a kind of silica-gel composition 比亚迪股份有限公司 2017-06-06 CN disclosed
CN-105960438-A Curable silicon composition, cured product thereof, and optical semiconductor device 道康宁东丽株式会社 2016-09-21 CN disclosed
WO-2016112487-A1 ORGANOPOLYSILOXANE PREPOLYMER AND CURABLE ORGANOPOLYSILOXANE COMPOSITION COMPRISING SAME HENKEL (CHINA) COMPANY LIMITED (CN) 2016-07-21 WO disclosed
WO-2016054781-A1 AN ORGANOPOLYSILOXANE PREPOLYMER AND A CURABLE ORGANOPOLYSILOXANE COMPOSITION COMPRISING THE SAME HENKEL (CHINA) COMPANY LIMITED (CN) 2016-04-14 WO disclosed
CN-105492539-A Curable silicone composition, cured product thereof, and optical semiconductor device DOW CORNING 2016-04-13 CN disclosed
US-8791221-B2 Addition-curable metallosiloxane compound DAICEL CORPORATION (JP) 2014-07-29 US disclosed
EP-2650319-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND Daicel Corporation (JP) 2013-10-16 EP disclosed
US-20130267653-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND DAICEL CORPORATION (JP) 2013-10-10 US disclosed
EP-2065455-B1 Pressure-sensitive adhesive tape NITTO DENKO CORP (JP) 2012-05-16 EP disclosed
US-20120015100-A1 Pressure-Sensitive Adhesive Tape NITTO DENKO CORPORATION (JP) 2012-01-19 US disclosed
EP-2383321-A2 Process for producing an adhesive composition and adhesive tape comprising an adhesive composition produced by said process Nitto Denko Corporation (JP) 2011-11-02 EP disclosed
US-20090142593-A1 PRESSURE-SENSITIVE ADHESIVE TAPE NITTO DENKO CORPORATION (JP) 2009-06-04 US disclosed
EP-2065455-A1 Pressure-sensitive adhesive tape NITTO DENKO CORPORATION (JP) 2009-06-03 EP disclosed
US-7015292-B2 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2006-03-21 US disclosed
US-20050038214-A1 Silicon-containing olefin copolymer, crosslinkable rubber composition thereof, and use thereof MITSUI CHEMICALS, INC. (JP) 2005-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130267653-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND B2M, MSI2, MNS1 TSHR 4702/4885ALDH1A1 2073/4885CA2 1322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.