Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19603220 | 0.86 | PTGDR2 (0.43) | CYP2A6CCR5HTR2ATRPM8ALDH1A1 | |
| SCHEMBL24102707 | 0.86 | PTGDR2 (0.43) | CYP2A6CCR5HTR2ATRPM8ALDH1A1 | |
| SCHEMBL30219182 | 0.86 | PTGDR2 (0.43) | CYP2A6CCR5HTR2ATRPM8ALDH1A1 | |
| SCHEMBL4477052 | 0.86 | CYP2A6 (0.43) | CYP2A6CCR5HTR2ATRPM8ALDH1A1 | |
| SCHEMBL16814166 | 0.83 | CYP2A6 (0.41) | CYP2A6CCR5HTR2ATRPM8TAAR1 | |
| SCHEMBL29676561 | 0.83 | CYP2A6 (0.41) | CYP2A6CCR5HTR2ATRPM8TAAR1 | |
| SCHEMBL16793967 | 0.83 | CYP2A6 (0.41) | CYP2A6CCR5HTR2ATRPM8TAAR1 | |
| SCHEMBL18719606 | 0.82 | CYP2A6 (0.47) | CYP2A6CCR5HTR2ATRPM8TAAR1 | |
| SCHEMBL28879858 | 0.82 | CYP2A6 (0.47) | CYP2A6CCR5HTR2ATRPM8TAAR1 | |
| SCHEMBL22715284 | 0.81 | DPP4 (0.40) | CYP2A6CCR5HTR2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010052448-A2 | FUSED PYRAZINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2010-05-14 | — | — | WO | disclosed |