Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.41 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13008122 | 1.00 | MEN1 (0.48) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL3392398 | 0.90 | HDAC3 (0.48) | MEN1KMT2AALDH1A1L3MBTL1POLB | |
| SCHEMBL13008155 | 0.90 | HDAC3 (0.48) | MEN1KMT2AALDH1A1L3MBTL1POLB | |
| SCHEMBL13403414 | 0.89 | HDAC3 (0.44) | ALDH1A1ALOX5L3MBTL1POLB | |
| SCHEMBL3392445 | 0.89 | HDAC3 (0.44) | ALDH1A1ALOX5L3MBTL1POLB | |
| SCHEMBL10593684 | 0.84 | ACE (0.56) | MEN1NPC1RAB9AKMT2AACE | |
| SCHEMBL10593686 | 0.84 | ACE (0.56) | MEN1NPC1RAB9AKMT2AACE | |
| SCHEMBL10594594 | 0.84 | ACE (0.56) | MEN1NPC1RAB9AKMT2AACE | |
| SCHEMBL8477698 | 0.80 | POLB (0.62) | NPC1RAB9AALDH1A1L3MBTL1POLB | |
| SCHEMBL8477697 | 0.80 | POLB (0.62) | NPC1RAB9AALDH1A1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737819-B1 | AMINO ACID AND PEPTIDE CONJUGATES OF ARYLALKYLIC ACIDS FOR COSMETIC USE | DSM IP ASSETS BV (NL) | 2010-12-22 | — | — | EP | disclosed |
| US-20100099727-A1 | Amino acid and peptide conjugates of arylalkylic acids for cosmetic use | DSM IP ASSETS B.V. (NL) | 2010-04-22 | — | — | US | disclosed |
| US-20080234344-A1 | Amino Acid and Peptide Conjugates of Arylalkylic Acids for Cosmetic Use | DSM IP ASSETS B.V. (NL) | 2008-09-25 | — | — | US | disclosed |
| EP-1737819-A1 | AMINO ACID AND PEPTIDE CONJUGATES OF ARYLALKYLIC ACIDS FOR COSMETIC USE | DSMIP Assets B.V. (NL) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005092850-A1 | AMINO ACID AND PEPTIDE CONJUGATES OF ARYLALKYLIC ACIDS FOR COSMETIC USE | DSM IP ASSETS B.V. (NL) | 2005-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234344-A1 | Amino Acid and Peptide Conjugates of Arylalkylic Acids for Cosmetic Use | NGLY1, HRH4, C3AR1 | MEN1 993/4885NPC1 1700/4885RAB9A 3397/4885 |
| US-20100099727-A1 | Amino acid and peptide conjugates of arylalkylic acids for cosmetic use | NGLY1, HRH4, C3AR1 | MEN1 993/4885NPC1 1700/4885RAB9A 3397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.