Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RARB | P10826 | 6/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795273 | 0.89 | RARB (0.53) | TDP1ALDH1A1RARBSRD5A2TP53 | |
| SCHEMBL10785469 | 0.87 | RARB (0.54) | TDP1ALDH1A1RARBSRD5A2TP53 | |
| SCHEMBL17541809 | 0.83 | TSHR (0.46) | TDP1ALDH1A1TSHR | |
| SCHEMBL29201805 | 0.83 | KMT2A (0.53) | ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL51938 | 0.80 | TDP1 (0.55) | TDP1ALDH1A1SRD5A2TP53TSHR | |
| Hydrogen Peroxide SCHEMBL28697848 | 0.79 | CYP1A2 (0.47) | TDP1ALDH1A1 | |
| SCHEMBL28601610 | 0.79 | CYP4A11 (0.58) | TDP1ALDH1A1TP53MAPTKMT2A | |
| SCHEMBL27862914 | 0.79 | FOLH1 (0.54) | TP53KMT2AFBP1 | |
| SCHEMBL27986594 | 0.79 | KCNJ1 (0.42) | ALDH1A1TSHRMAPTKMT2AMEN1 | |
| SCHEMBL70166 | 0.79 | TSHR (0.67) | ALDH1A1RARBSRD5A2TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212375-B1 | MODERATED REDUCTION REACTIONS FOR PRODUCING ARYLHYDROXYLAMINES | MicroSi, Inc. (a Delaware corporation) (US) | 1993-06-16 | — | — | EP | claimed |
| US-4723030-A | ACID CATALYTIC HYDROGENATION OF NITROAROMATIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 1988-02-02 | — | — | US | claimed |
| US-4709107-A | Process for producing nitrones | GENERAL ELECTRIC COMPANY (US) | 1987-11-24 | — | — | US | claimed |
| EP-0212375-A1 | Moderated reduction reactions for producing arylhydroxylamines | MicroSi, Inc. (a Delaware corporation) (US) | 1987-03-04 | — | — | EP | claimed |
| CN-117659906-A | Packaging adhesive film composition, packaging adhesive film and application | 福斯特(滁州)新材料有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-105418431-A | Synthesis method of 2-chloro-6-bromo-p-nitrobenzoic acid | DING YUQIN | 2016-03-23 | — | — | CN | disclosed |
| CN-102276550-A | Method for synthesizing 2-aryl nitrile thiazole derivative and intermediate thereof | — | 2011-12-14 | — | — | CN | disclosed |
| US-20100009269-A1 | HOLOGRAPHIC RECORDING MEDIA | GENERAL ELECTRIC COMPANY (US) | 2010-01-14 | — | — | US | disclosed |
| US-20100010262-A1 | COMPOSITIONS AND METHOD FOR MAKING THEREOF | GENERAL ELECTRIC COMPANY (US) | 2010-01-14 | — | — | US | disclosed |
| CN-101606522-A | N-aroyl tetrahydropyrimidineinsecticide insecticide and preparation method thereof | UNIV SHANGHAI (CN) | 2009-12-23 | — | — | CN | disclosed |
| CN-1161337-C | Chinolinelone derivative, its prepn. method and antiabnormal reaction agent | ���ձ���ī��ѧ��ҵ��ʽ���� | 2004-08-11 | — | — | CN | disclosed |
| US-6207794-B1 | USING PHOSPHAZENIUM CATALYST | MITSUI CHEMICAL, INC. (JP) | 2001-03-27 | — | — | US | disclosed |
| CN-1221738-A | Chinolinelone derivative, its prepn. method and antiabnormal reaction agent | DAINIPPON INK & CHEMICALS (JP) | 1999-07-07 | — | — | CN | disclosed |
| EP-0916686-A1 | POLYOXYALKYLENEPOLYOLS, DERIVATIVES THEREOF, AND PROCESS FOR PRODUCING THE POLYOXYALKYLENEPOLYOLS | Mitsui Chemicals, Inc. (JP) | 1999-05-19 | — | — | EP | disclosed |
| EP-0212375-B1 | MODERATED REDUCTION REACTIONS FOR PRODUCING ARYLHYDROXYLAMINES | MicroSi, Inc. (a Delaware corporation) (US) | 1993-06-16 | — | — | EP | disclosed |
| US-4723030-A | ACID CATALYTIC HYDROGENATION OF NITROAROMATIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 1988-02-02 | — | — | US | disclosed |
| US-4709107-A | Process for producing nitrones | GENERAL ELECTRIC COMPANY (US) | 1987-11-24 | — | — | US | disclosed |
| EP-0212375-A1 | Moderated reduction reactions for producing arylhydroxylamines | MicroSi, Inc. (a Delaware corporation) (US) | 1987-03-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100010262-A1 | COMPOSITIONS AND METHOD FOR MAKING THEREOF | C5, C1R, CBR3 | TDP1 2905/4885ALDH1A1 3712/4885RARB 1672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.