Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.44 |
| ▸ | HTR2B | P41595 | 7/20 | 0.44 |
| ▸ | HTR2A | P28223 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1262509 | 0.98 | HTR2C (0.43) | HTR2CHTR2BHTR2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1970467 | 0.80 | HTR2A (0.36) | HTR2CHTR2BHTR2ASMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1262763 | 0.78 | HTR2A (0.35) | HTR2CHTR2BHTR2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL1967719 | 0.78 | HTR2A (0.34) | HTR2CHTR2BHTR2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL17297725 | 0.78 | HTR2C (0.44) | HTR2CHTR2BHTR2APARP1TNKS2 | |
| SCHEMBL25803064 | 0.78 | SMN1; SMN2 (0.50) | HTR2CHTR2BHTR2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL8257616 | 0.77 | HTR2A (0.46) | HTR2CHTR2BHTR2ASMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1261973 | 0.76 | HTR2A (0.33) | HTR2CHTR2BHTR2ASMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1263416 | 0.76 | HTR2A (0.45) | HTR2CHTR2BHTR2ASMN1; SMN2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1262608 | 0.75 | HTR2A (0.36) | HTR2CHTR2BHTR2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863812-B1 | DIPEPTIDYL PEPTIDASE-IV INHIBITING COMPOUNDS, METHODS OF PREPARING THE SAME, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE AGENT | LG LIFE SCIENCES LTD (KR) | 2010-07-14 | — | — | EP | disclosed |