Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CDC25B | P30305 | 3/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | WDR5 | P61964 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31256575 | 1.00 | NR4A1 (0.57) | NR4A1NR4A2NR4A3CYP1A2CYP2A6 | |
| SCHEMBL14852738 | 0.85 | KDM4E (0.47) | NR4A1NR4A2NR4A3CYP1A2KDM4E | |
| SCHEMBL6362640 | 0.85 | CYP1A2 (0.53) | NR4A1NR4A2NR4A3CYP1A2CYP2A6 | |
| SCHEMBL12316910 | 0.83 | KDM4E (0.53) | NR4A1NR4A2NR4A3CYP1A2CYP2A6 | |
| SCHEMBL17919668 | 0.80 | PLK1 (0.64) | CYP1A2CYP2A6KDM4EKMT2AALDH1A1 | |
| SCHEMBL28245095 | 0.80 | CYP1A2 (0.48) | NR4A1NR4A2NR4A3CYP1A2CYP2A6 | |
| SCHEMBL29254661 | 0.80 | CYP1A2 (0.48) | NR4A1NR4A2NR4A3CYP1A2CYP2A6 | |
| SCHEMBL31533158 | 0.80 | NR4A1 (0.61) | NR4A1NR4A2NR4A3CYP1A2KDM4E | |
| SCHEMBL344157 | 0.79 | PTPN1 (0.66) | NR4A1NR4A2NR4A3CYP1A2KDM4E | |
| SCHEMBL31522164 | 0.79 | PTPN1 (0.66) | NR4A1NR4A2NR4A3CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244167-B1 | IMPROVED PROCESS FOR PREPARING POLY (ARYL ETHERS) AND POLY (ARYL ETHER KETONES) | AMOCO CORPORATION (US) | 1990-04-04 | — | — | EP | claimed |
| US-4748227-A | Process for preparing poly(aryl ether)ketones using a sodium carbonate/organic acid salt catalyst | AMOCO CORPORATION (US) | 1988-05-31 | — | — | US | claimed |
| EP-0244167-A1 | Improved process for preparing poly (aryl ethers) and poly (aryl ether ketones) | AMOCO CORPORATION (US) | 1987-11-04 | — | — | EP | claimed |
| US-20230330099-A1 | SUBSTITUTED INDOLE MCL-1 INHIBITORS | VANDERBILT UNIVERSITY | 2023-10-19 | — | — | US | disclosed |
| US-20220185785-A1 | INHIBITORS OF CD40-CD154 BINDING | TONIX Pharmaceuticals Holding Corp (US) | 2022-06-16 | — | — | US | disclosed |
| EP-3230339-B1 | EPOXY RESIN COMPOSITION, PREPREG, FIBER-REINFORCED PLASTIC MATERIAL, AND MANUFACTURING METHOD FOR FIBER-REINFORCED PLASTIC MATERIAL | TORAY INDUSTRIES (JP) | 2022-03-23 | — | — | EP | disclosed |
| EP-3952853-A1 | INHIBITORS OF CD40-CD154 BINDING | Tonix Pharmaceuticals Holding Corp. (US) | 2022-02-16 | — | — | EP | disclosed |
| WO-2020210831-A1 | INHIBITORS OF CD40-CD154 BINDING | TONIX Pharmaceuticals Holding Corp (US) | 2020-10-15 | — | — | WO | disclosed |
| CN-107001594-B | Composition epoxy resin, prepreg, the manufacturing method of fiber reinforced plastic materials and fiber reinforced plastic materials | 东丽株式会社 | 2019-07-23 | — | — | CN | disclosed |
| US-10005721-B2 | Dimethylbenzoic acid compounds | ELI LILLY AND COMPANY (US) | 2018-06-26 | — | — | US | disclosed |
| US-20170362376-A1 | EPOXY RESIN COMPOSITION, PREPREG, FIBER-REINFORCED PLASTIC MATERIAL, AND MANUFACTURING METHOD FOR FIBER-REINFORCED PLASTIC MATERIAL | TORAY INDUSTRIES, INC. (JP) | 2017-12-21 | — | — | US | disclosed |
| US-4061661-A | Δ9(11) -5α-20-KETO STEROIDS AND PROCESS FOR THEIR PRODUCTION | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-12-06 | — | — | US | disclosed |
| US-4032540-A | BENZOPYRAN DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-06-28 | — | — | US | disclosed |
| US-4021458-A | Process for the preparation of 3-hemisulfate-17α-hydroxy steroids | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-05-03 | — | — | US | disclosed |
| US-4016269-A | 17α-HYDROXY-1,3,5(10),15-ESTRATETRAENES AND PROCESS FOR THEIR PRODUCTION | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |
| US-4012510-A | Novel methylene steroids | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-03-15 | — | — | US | disclosed |
| US-4011314-A | FOR TREATING ESTROGEN DEFICIENCY | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-03-08 | — | — | US | disclosed |
| US-4001298-A | RADIOPAQUE AGENTS | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-01-04 | — | — | US | disclosed |
| US-3962280-A | PROCESS FOR PREPARING BENZOPYRAN DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-06-08 | — | — | US | disclosed |
| US-3939204-A | IODO SUBST. DICARBOXYLIC ACID ANTILIDES | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230330099-A1 | SUBSTITUTED INDOLE MCL-1 INHIBITORS | MCL1, BCL2L1, BCL9 | NR4A1 3610/4885NR4A2 2684/4885NR4A3 3103/4885 |
| US-20220185785-A1 | INHIBITORS OF CD40-CD154 BINDING | CD40LG, CD40, CD4 | NR4A1 235/4885NR4A2 472/4885NR4A3 191/4885 |
| US-10005721-B2 | Dimethylbenzoic acid compounds | PTGER4, EDNRB, EPB41 | NR4A1 54/4885NR4A2 102/4885NR4A3 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.