Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 19/20 | 0.67 |
| ▸ | PPARG | P37231 | 2/20 | 0.66 |
| ▸ | PPARA | Q07869 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7620234 | 0.90 | PPARA (0.62) | FFAR1PPARGPPARA | |
| SCHEMBL1508324 | 0.85 | FFAR1 (0.78) | FFAR1PPARG | |
| SCHEMBL4797636 | 0.82 | FFAR1 (0.52) | FFAR1PPARGPPARA | |
| SCHEMBL5993840 | 0.81 | PPARA (0.68) | FFAR1PPARGPPARA | |
| SCHEMBL5365643 | 0.81 | PPARA (0.67) | FFAR1PPARGPPARA | |
| Tesaglitazar SCHEMBL3162078 | 0.80 | PPARA (1.00) | PPARGPPARA | |
| Tesaglitazar SCHEMBL13602606 | 0.80 | PPARA (1.00) | PPARGPPARA | |
| Tesaglitazar SCHEMBL16594 | 0.80 | PPARA (1.00) | PPARGPPARA | |
| SCHEMBL5368994 | 0.80 | PPARA (1.00) | PPARGPPARA | |
| Tesaglitazar SCHEMBL600880 | 0.80 | PPARA (1.00) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100076037-A1 | Methods of Treating Neuropathic Pain with Agonists of PPAR-gamma | AESTUS THERAPEUTICS, INC. | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076037-A1 | Methods of Treating Neuropathic Pain with Agonists of PPAR-gamma | PPARG, PPARA, PPARD | FFAR1 58/4885PPARG 1/4885PPARA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.