SCHEMBL3392834

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3391260	0.99	HTT (0.56)	HTTTSHRFAAHCYP3A4CYP2D6
	SCHEMBL3396988	0.89	HTT (0.54)	HTTTSHRFAAHCYP3A4CYP2D6
	SCHEMBL3395382	0.87	HTT (0.57)	HTTMEN1KMT2ACACNA1CCACNA2D1
	SCHEMBL3395377	0.87	HTT (0.57)	HTTTSHRFAAHCYP3A4CYP2D6
	SCHEMBL3396198	0.86	HTT (0.56)	HTTTSHRFAAHCYP3A4CYP2D6
	SCHEMBL3396526	0.86	HTT (0.56)	HTTMEN1KMT2ACACNA1CCACNA2D1
	SCHEMBL3394392	0.85	TSHR (0.55)	HTTTSHRFAAHCYP3A4CYP2D6
	SCHEMBL3391930	0.85	HTT (0.56)	HTTTSHRFAAHCYP3A4CYP2D6
	SCHEMBL3558938	0.84	HTT (0.55)	HTTTSHRFAAHCYP3A4CYP2D6
	SCHEMBL3432018	0.81	HTT (0.80)	HTTRAB9AMEN1KMT2ACACNA1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.