SCHEMBL33929

SCHEMBL33929

Nc1cccc(F)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30081430 1.00
Fluoride SCHEMBL27681365 0.97 CYP3A4 (0.58)
SCHEMBL357209 0.97
Hydrochloric Acid SCHEMBL593417 0.97
Hydrochloric Acid SCHEMBL31174566 0.97
Bromide SCHEMBL25169253 0.97
Water SCHEMBL27940487 0.97
Hydrochloric Acid SCHEMBL4381072 0.97 CYP3A4 (0.58)
Nitrogen SCHEMBL924838 0.95 CYP3A4 (0.55)
Formaldehyde SCHEMBL28172434 0.92 CYP3A4 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7934 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010953-A Pyrazolo [1, 5-alpha ] pyrimidine compound, and synthetic method and application thereof 豫北医学院 2026-05-12 CN claimed
US-20260015369-A1 PEROVSKITE SYSTEM INCLUDING ANILINIUM-BASED LIGANDS AND RELATED PEROVSKITE SOLAR CELL THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2026-01-15 US claimed
CN-120136781-A ROR 1-targeted inhibitor and synthesis method and application thereof 北京大学 2025-06-13 CN claimed
CN-120117998-A Preparation method of apatamide intermediate N-methyl-2-fluoro-4-aminobenzamide 成都博腾药业有限公司 2025-06-10 CN claimed
CN-120004697-A Preparation method of OrgVO material and application of OrgVO material as secondary battery anode material 同济大学 2025-05-16 CN claimed
CN-119977819-A Organic electric energy transfer eutectic crystal with near infrared light thermal characteristics and preparation method of light heat storage fiber thereof 苏州大学 2025-05-13 CN claimed
CN-119751460-A Triazolopyrimidine antitumor compound and preparation method and application thereof 江苏海洋大学 2025-04-04 CN claimed
CN-119752315-A Closed material for underground space energy storage and preparation method thereof 中煤科工开采研究院有限公司 2025-04-04 CN claimed
CN-119733389-A Preparation method of ultralow-pressure sea water desalination reverse osmosis composite membrane 新疆大学 2025-04-01 CN claimed
CN-119707773-A Preparation method and application of maleimide structure-containing compound 中国农业大学 2025-03-28 CN claimed
EP-0667337-A1 Method for preparing fluoroanilines HOECHST AKTIENGESELLSCHAFT (DE) 1995-08-16 EP claimed
EP-0514472-B1 HALOGENATION OF AROMATIC AMINE COMPOUNDS MALLINCKRODT INC (US) 1994-09-28 EP claimed
US-5315043-A Potassium, cesium, rubidium fluorides and hydrofluoric acid E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-05-24 US claimed
WO-1993014062-A1 ANTHELMINTIC β-KETOAMIDES THE UPJOHN COMPANY (US) 1993-07-22 WO claimed
EP-0514472-A1 HALOGENATION OF AROMATIC AMINE COMPOUNDS. MALLINCKRODT INC (US) 1992-11-25 EP claimed
US-5149875-A Reacting in presence of quaternary ammonium halide MALLINCKRODT SPECIALTY CHEMICALS COMPANY (US) 1992-09-22 US claimed
WO-1991011430-A1 HALOGENATION OF AROMATIC AMINE COMPOUNDS MALLINCKRODT, INC. (US) 1991-08-08 WO claimed
EP-0030009-B1 NEW DERIVATIVES OF THE 9-CIS-6,6'-DIAPO-PSI,PSI-CAROTENEDIOIC ACID, PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME Simes S.p.A. (IT) 1983-05-11 EP claimed
US-4343951-A Method for the preparation of fluoroaniline HOOKER CHEMICALS & PLASTICS CORP. (US) 1982-08-10 US claimed
EP-0030009-A1 New derivatives of the 9-cis-6,6'-diapo-psi,psi-carotenedioic acid, preparation thereof and pharmaceutical compositions containing same Simes S.p.A. (IT) 1981-06-10 EP claimed