Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.95 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28167488 | 1.00 | PARP1 (0.95) | PARP1OXTRCA1CA2PNMT | |
| SCHEMBL29429329 | 1.00 | PARP1 (0.95) | PARP1OXTRCA1CA2PNMT | |
| Iodide SCHEMBL7226882 | 0.98 | PARP1 (0.91) | PARP1OXTRCA1CA2PNMT | |
| SCHEMBL28243677 | 0.98 | PARP1 (0.91) | PARP1OXTRCA1CA2PNMT | |
| Hydrochloric Acid SCHEMBL27599345 | 0.98 | PARP1 (1.00) | PARP1OXTRCA1CA2PNMT | |
| Hydrochloric Acid SCHEMBL7007870 | 0.98 | PARP1 (1.00) | PARP1OXTRCA1CA2PNMT | |
| Bromide SCHEMBL7236242 | 0.98 | PARP1 (0.91) | PARP1OXTRCA1CA2PNMT | |
| Bromide SCHEMBL19031040 | 0.98 | PARP1 (0.91) | PARP1OXTRCA1CA2PNMT | |
| Formaldehyde SCHEMBL27966942 | 0.94 | PARP1 (0.84) | PARP1OXTRCA1CA2PNMT | |
| SCHEMBL27864562 | 0.92 | PARP1 (0.81) | PARP1OXTRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 6407 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4396191-B1 | COMPOUNDS USEFUL IN MODULATION OF AHR SIGNALLING | JAGUAHR THERAPEUTICS PTE LTD (SG) | 2026-02-18 | — | — | EP | claimed |
| EP-4611899-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | Petra Pharma Corporation (US) | 2025-09-10 | — | — | EP | claimed |
| US-20250154109-A1 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC | 2025-05-15 | — | — | US | claimed |
| WO-2025076059-A1 | ROCAGLATE DERIVATIVES AND USES THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2025-04-10 | — | — | WO | claimed |
| CN-117567553-B | 2-Thr-dihydroisoquinoline-3S-formyl-AA as IL-2 agonist, and preparation and antitumor application thereof | 首都医科大学 | 2025-03-28 | — | — | CN | claimed |
| WO-2025029890-A1 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2025-02-06 | — | — | WO | claimed |
| US-12195445-B2 | 2-amino-N-heteroaryl-nicotinamides as Nav1.8 inhibitors | MERCK SHARP & DOHME LLC (US) | 2025-01-14 | — | — | US | claimed |
| EP-4472966-A2 | SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | Latigo Biotherapeutics, Inc. (US) | 2024-12-11 | — | — | EP | claimed |
| US-20240355476-A1 | METHODS AND COMPOSITIONS RELATED TO TRIPLE-NEGATIVE BREAST CANCER | THE UNIVERSITY OF CHICAGO (US) | 2024-10-24 | — | — | US | claimed |
| CN-118221636-A | Substituted dihydro isoquinoline derivative, preparation method and application thereof | 浙江省化工研究院有限公司 | 2024-06-21 | — | — | CN | claimed |
| WO-1986000897-A1 | NOVEL RADIOPHARMACEUTICALS AND CHELATING AGENTS USEFUL IN THEIR PREPARATION | UNIVERSITY OF FLORIDA (US) | 1986-02-13 | — | — | WO | claimed |
| WO-1985003937-A1 | BRAIN-SPECIFIC ANALOGUES OF CENTRALLY ACTING AMINES | UNIVERSITY OF FLORIDA (US) | 1985-09-12 | — | — | WO | claimed |
| US-4540564-A | DIHYDROPYRIDINE AND/OR PYRIDINIUM SALT REDOX CARRIER | UNIVERSITY OF FLORIDA (US) | 1985-09-10 | — | — | US | claimed |
| EP-0028959-B1 | 5,8,13,13A-TETRAHYDRO-6H-DIBENZO(A,G)QUINOLIZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | U.R.P.H.A. (FR) | 1985-01-30 | — | — | EP | claimed |
| EP-0028279-B1 | PHTHALIDE-ISOQUINOLINE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN MEDICAMENTS | CALAIRE CHIMIE S.A. (FR) | 1983-02-16 | — | — | EP | claimed |
| EP-0028959-A1 | 5,8,13,13a-Tetrahydro-6H-dibenzo(a,g)quinolizine derivatives, process for their preparation and pharmaceutical compositions containing them | U.R.P.H.A. (FR) | 1981-05-20 | — | — | EP | claimed |
| EP-0028279-A1 | Phthalide-isoquinoline derivatives, their preparation and their use in medicaments | CALAIRE CHIMIE S.A. (FR) | 1981-05-13 | — | — | EP | claimed |
| US-4200754-A | Method for preparing 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline | SMITHKLINE CORPORATION (US) | 1980-04-29 | — | — | US | claimed |
| US-4013468-A | Method of hardening a protein-containing layer of a silver halide photographic material with an alkyl ester of 1,2-dihydroquinoline-N-carboxylic acid | AGFA-GEVAERT, A.G. (DT) | 1977-03-22 | — | — | US | claimed |
| US-3983122-A | FROM CYCLOALKENYL KETONE AND DIHYDROISOQUINOLINE, ANTIDEPRESSANT | RICHARDSON-MERRELL INC. (US) | 1976-09-28 | — | — | US | claimed |