Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.78 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.78 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.78 |
| ▸ | PREP | P48147 | 1/20 | 0.47 |
| ▸ | FAP | Q12884 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3759598 | 1.00 | DPP4 (0.78) | DPP4DPP8DPP9PREPFAP | |
| SCHEMBL18098588 | 1.00 | DPP4 (0.78) | DPP4DPP8DPP9PREPFAP | |
| SCHEMBL13000720 | 1.00 | DPP4 (0.78) | DPP4DPP8DPP9PREPFAP | |
| Cadaverine Tartrate SCHEMBL3393637 | 0.94 | DPP4 (0.69) | DPP4DPP8DPP9PREP | |
| Cadaverine Tartrate SCHEMBL3759430 | 0.94 | DPP4 (0.69) | DPP4DPP8DPP9PREP | |
| SCHEMBL13070580 | 0.89 | DPP4 (0.70) | DPP4DPP8DPP9 | |
| SCHEMBL13057146 | 0.89 | DPP4 (0.73) | DPP4DPP8DPP9 | |
| SCHEMBL3759440 | 0.88 | DPP4 (1.00) | DPP4DPP8DPP9PREPFAP | |
| SCHEMBL18098616 | 0.88 | DPP4 (1.00) | DPP4DPP8DPP9PREPFAP | |
| SCHEMBL13000689 | 0.88 | DPP4 (1.00) | DPP4DPP8DPP9PREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246347-B1 | DICYCLOAZAALKANE DERIVATES, PREPARATION PROCESSES AND MEDICAL USES THEREOF | SHANGHAI HENGRUI PHARM CO LTD (CN) | 2016-09-28 | — | — | EP | disclosed |
| EP-2246347-A1 | DICYCLOAZAALKANE DERIVATES, PREPARATION PROCESSES AND MEDICAL USES THEREOF | Shanghai Hengrui Pharmaceutical Co. Ltd. (CN) | 2010-11-03 | — | — | EP | disclosed |