⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL761496 | 0.80 | CYP3A4 (0.43) | — | |
| SCHEMBL9413861 | 0.78 | — | — | |
| SCHEMBL9543820 | 0.78 | — | — | |
| SCHEMBL1288180 | 0.76 | — | — | |
| SCHEMBL30940 | 0.76 | TSHR (0.59) | — | |
| SCHEMBL27511292 | 0.74 | TSHR (0.41) | — | |
| SCHEMBL27290907 | 0.74 | TSHR (0.46) | — | |
| SCHEMBL18636049 | 0.73 | — | — | |
| SCHEMBL338964 | 0.73 | — | — | |
| SCHEMBL7707206 | 0.73 | CYP3A4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108553-B | Process for preparing diarylthiohydantoin compounds | 阿拉贡药品公司 | 2020-04-28 | — | — | CN | claimed |
| WO-2013164856-A1 | A PROCESS FOR PREPARING INTERMEDIATES OF 10-PROPARGYL-10-DEAZAAMINOPTERIN (PRALATREXATE) SYNTHESIS AND THE INTERMEDIATES THEREOF | AVRA LABORATORIES PRIVATE LIMITED (IN) | 2013-11-07 | — | — | WO | claimed |
| EP-0712847-A1 | IMIDAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND PEST CONTROL DRUG | NIPPON SODA CO., LTD. (JP) | 1996-05-22 | — | — | EP | claimed |
| EP-0342849-A2 | Intermediates for preparing 1,4-dihydro-4-oxo-quinoline-3-carboxylic acid esters | PFIZER INC. (US) | 1989-11-23 | — | — | EP | claimed |
| EP-0323885-A1 | New chemical process | MAY & BAKER LIMITED (GB) | 1989-07-12 | — | — | EP | claimed |
| US-4539422-A | Process for preparing cephalosporin intermediates | ELI LILLY AND COMPANY (US) | 1985-09-03 | — | — | US | claimed |
| EP-0136145-A2 | Process for preparing alkyl cyanoformates | ELI LILLY AND COMPANY (US) | 1985-04-03 | — | — | EP | claimed |
| EP-0023938-B1 | PREPARATION OF PYRROLE-2-ACETATES | McNeilab, Inc. (US) | 1983-07-20 | — | — | EP | claimed |
| US-4316037-A | N-Benzyl and N-substituted benzyl tetrazole-5-carboxylic acids and the preparation thereof | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-02-16 | — | — | US | claimed |
| JP-57067545-A | — | — | None | — | — | JP | disclosed |
| JP-2225452-A | — | — | None | — | — | JP | disclosed |
| JP-2225454-A | — | — | None | — | — | JP | disclosed |
| JP-1213271-A | — | — | None | — | — | JP | disclosed |
| CN-111315739-B | Pyrimidine derivatives | 豪夫迈·罗氏有限公司 | 2023-12-05 | — | — | CN | disclosed |
| US-4316037-A | N-Benzyl and N-substituted benzyl tetrazole-5-carboxylic acids and the preparation thereof | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-02-16 | — | — | US | disclosed |
| US-4316037-A | N-Benzyl and N-substituted benzyl tetrazole-5-carboxylic acids and the preparation thereof | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-02-16 | — | — | US | disclosed |
| US-4134981-A | ANTIALLERGENS | PFIZER INC. (US) | 1979-01-16 | — | — | US | disclosed |
| US-4120962-A | Fused pyrimidin-4(3H)-ones as antiallergy agents | PFIZER INC. (US) | 1978-10-17 | — | — | US | disclosed |
| US-4044134-A | FUSED WITH QUINOLINE OR PYRIDINE, 2-METHYL, ETHYL, OR ACETYL GROUP | PFIZER INC. (US) | 1977-08-23 | — | — | US | disclosed |
| US-3974161-A | Fused pyrimidin-4(3H)-ones as antiallergy agents | PFIZER INC. (US) | 1976-08-10 | — | — | US | disclosed |