Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3144383 | 0.88 | SLC2A1 (0.44) | SLC2A1KCNH2HTR1ADRD2 | |
| SCHEMBL3144391 | 0.88 | SLC2A1 (0.44) | SLC2A1KCNH2HTR1ADRD2 | |
| SCHEMBL3224839 | 0.85 | SLC2A1 (0.47) | SLC2A1KCNH2HTR1ADRD2 | |
| SCHEMBL3676325 | 0.85 | SLC2A1 (0.36) | SLC2A1KCNH2HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL3149069 | 0.84 | SLC2A1 (0.46) | SLC2A1KCNH2 | |
| SCHEMBL3149951 | 0.80 | SLC2A1 (0.43) | SLC2A1KCNH2HTR1ADRD2 | |
| SCHEMBL3142143 | 0.80 | SLC2A1 (0.43) | SLC2A1KCNH2HTR1ADRD2 | |
| SCHEMBL3155543 | 0.80 | SLC2A1 (0.54) | SLC2A1KCNH2 | |
| SCHEMBL4796885 | 0.79 | SLC2A1 (0.40) | SLC2A1KCNH2 | |
| SCHEMBL17627903 | 0.79 | KCNH2 (0.45) | SLC2A1KCNH2HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2136807-B1 | PYRROLO (3, 2, 1-IJ) QUINOLINE-4-ONE DERIVATIVES FOR TREATING TUBERCULOSIS | GLAXO GROUP LTD (GB) | 2010-11-03 | — | — | EP | disclosed |
| EP-2136807-A1 | PYRROLO (3, 2, 1-IJ) QUINOLINE-4-ONE DERIVATIVES FOR TREATING TUBERCULOSIS | Glaxo Group Limited (GB) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008125594-A1 | PYRROLO (3, 2, 1-IJ) QUINOLINE-4-ONE DERIVATIVES FOR TREATING TUBERCULOSIS | GLAXO GROUP LIMITED (GB) | 2008-10-23 | — | — | WO | disclosed |