Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27578927 | 1.00 | TSHR (0.52) | TSHRLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL113730 | 1.00 | TSHR (0.52) | TSHRLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL27991539 | 1.00 | TSHR (0.52) | TSHRLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL7034842 | 1.00 | TSHR (0.52) | TSHRLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL1667200 | 1.00 | TSHR (0.52) | TSHRLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL4613430 | 1.00 | TSHR (0.52) | TSHRLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL8002999 | 1.00 | TSHR (0.52) | TSHRLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL316565 | 1.00 | TSHR (0.52) | TSHRLMNAALDH1A1HSD17B10MEN1 | |
| Ammonia Solution, Strong SCHEMBL27563564 | 0.97 | TSHR (0.50) | TSHRLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL1664849 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100003431-A1 | COMPOSITE MATERIALS | RAYBUCK JOHN | 2010-01-07 | — | — | US | disclosed |
| CN-101384673-A | Organoclay suitable for use in halogenated resin and composite systems thereof | ELEMENTIS SPECIALTIES INC (US) | 2009-03-11 | — | — | CN | disclosed |
| US-4771088-A | ETHOXYLATED QUATERNARY AMMONIUM CHLORIDE COMPOUND | THE GLIDDEN COMPANY (US) | 1988-09-13 | — | — | US | disclosed |