Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tetradecane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 7/20 | 0.44 |
| ▸ | CA1 | P00915 | 6/20 | 0.44 |
| ▸ | CA9 | Q16790 | 6/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexadecane SCHEMBL27472157 | 1.00 | RECQL (0.61) | RECQLTSHRGLAHPGDMAPK1 | |
| Sulfuric Acid SCHEMBL29027387 | 1.00 | RECQL (0.61) | RECQLTSHRGLAHPGDMAPK1 | |
| Decane SCHEMBL3962532 | 1.00 | RECQL (0.61) | RECQLTSHRGLAHPGDMAPK1 | |
| Tetradecane SCHEMBL2679723 | 1.00 | RECQL (0.61) | RECQLTSHRGLAHPGDMAPK1 | |
| Octane SCHEMBL7174098 | 1.00 | RECQL (0.61) | RECQLTSHRGLAHPGDMAPK1 | |
| Pentadecane SCHEMBL13370387 | 1.00 | RECQL (0.61) | RECQLTSHRGLAHPGDMAPK1 | |
| Heptane SCHEMBL25268199 | 1.00 | RECQL (0.61) | RECQLTSHRGLAHPGDMAPK1 | |
| Sulfuric Acid SCHEMBL29238029 | 1.00 | RECQL (0.61) | RECQLTSHRGLAHPGDMAPK1 | |
| Dodecane SCHEMBL5903124 | 1.00 | RECQL (0.61) | RECQLTSHRGLAHPGDMAPK1 | |
| Sulfuric Acid SCHEMBL27540382 | 1.00 | RECQL (0.61) | RECQLTSHRGLAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140155443-A1 | COMPOSITIONS AND METHODS OF TREATMENT FOR PSORIASIS | DASCALU AVI (IL) | 2014-06-05 | — | — | US | disclosed |
| EP-2204158-A1 | TWO-PART HAIR DYE | Kao Corporation (JP) | 2010-07-07 | — | — | EP | disclosed |