SCHEMBL3394418

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3396540	0.86	CACNA2D1 (1.00)	CACNA2D1CACNA1BCACNB1CACNA1CHTT
	SCHEMBL3398085	0.81	CACNA2D1 (0.78)	CACNA2D1CACNA1BCACNB1CACNA1COPRM1
	SCHEMBL17512449	0.80	CACNA2D1 (0.81)	CACNA2D1CACNA1BCACNB1CACNA1CHTT
	SCHEMBL3396530	0.80	CACNA2D1 (0.86)	CACNA2D1CACNA1BCACNB1CACNA1CHTT
	SCHEMBL3395395	0.79	CACNA2D1 (1.00)	CACNA2D1CACNA1BCACNB1CACNA1CCNR1
	SCHEMBL3396514	0.77	CACNA2D1 (1.00)	CACNA2D1CACNA1BCACNB1CACNA1CCNR1
	SCHEMBL5543965	0.76	CACNA2D1 (0.77)	CACNA2D1CACNA1BCACNB1CACNA1COPRM1
	SCHEMBL8692759	0.76	KMT2A (0.59)	OPRM1OPRD1OPRK1OPRL1FNTA
	SCHEMBL3396784	0.76	CACNA2D1 (1.00)	CACNA2D1CACNA1BCACNB1CACNA1COPRM1
	SCHEMBL3395370	0.76	CACNA2D1 (0.78)	CACNA2D1CACNA1BCACNB1CACNA1COPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.