SCHEMBL3394565

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3395684	0.92	EGFR (0.85)	EGFRERBB2
	SCHEMBL16075707	0.90	EGFR (1.00)	EGFRERBB2
	SCHEMBL29752064	0.89	EGFR (1.00)	EGFRERBB2
	SCHEMBL3391122	0.89	EGFR (1.00)	EGFRERBB2
	SCHEMBL22598583	0.88	EGFR (1.00)	EGFRERBB2
	SCHEMBL30264412	0.88	EGFR (0.83)	EGFRERBB2
	SCHEMBL3391873	0.88	EGFR (0.86)	EGFRERBB2
	SCHEMBL3391777	0.87	EGFR (0.88)	EGFRERBB2
	SCHEMBL3432391	0.87	EGFR (0.88)	EGFRERBB2
	SCHEMBL3388106	0.87	EGFR (0.88)	EGFRERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.