Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL5836390 | 1.00 | CA4 (0.60) | — | |
| Bicarbonate SCHEMBL23849739 | 1.00 | CA4 (0.60) | — | |
| Bicarbonate SCHEMBL3899 | 1.00 | — | — | |
| Bicarbonate SCHEMBL486045 | 1.00 | CA4 (0.60) | — | |
| Bicarbonate SCHEMBL10893826 | 0.94 | — | — | |
| Bicarbonate SCHEMBL21359709 | 0.94 | CA4 (0.55) | — | |
| Bicarbonate SCHEMBL8712057 | 0.94 | — | — | |
| Bicarbonate SCHEMBL22687542 | 0.94 | — | — | |
| Bicarbonate SCHEMBL9511277 | 0.94 | — | — | |
| Bicarbonate SCHEMBL5173075 | 0.94 | CA4 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8889184-B2 | Particulate form of a pharmaceutical composition which is easy to swallow | LOSAN PHARMA GMBH (DE) | 2014-11-18 | — | — | US | disclosed |
| EP-2051693-B1 | PHARMACEUTICAL COMPOSITIONS EASY TO SWALLOW, NOT CAUSING ANY UNPLEASANT ORAL SENSATION AND COMPRISING PARTICLES WITH AN ACTIVE PRINCIPLE | LOSAN PHARMA GMBH (DE) | 2010-10-13 | — | — | EP | disclosed |
| EP-2051693-A1 | PHARMACEUTICAL COMPOSITIONS EASY TO SWALLOW, NOT CAUSING ANY UNPLEASANT ORAL SENSATION AND COMPRISING PARTICLES WITH AN ACTIVE PRINCIPLE | Losan Pharma GmbH (DE) | 2009-04-29 | — | — | EP | disclosed |
| US-20080063713-A1 | Outermost coating layer contains neutral methacrylic acid esters copolymer capable of forming a gel with water; sodium glycin carbonate releasing carbon dioxide; adjuvants; promoting salivation with sucrose, glucose, maltodextrin, sorbitol, mannitol, xylitol, maltitol; easily ingestible without water | LOSAN PHARMA GMBH (DE) | 2008-03-13 | — | — | US | disclosed |
| WO-2008019854-A1 | PHARMACEUTICAL COMPOSITIONS EASY TO SWALLOW, NOT CAUSING ANY UNPLEASANT ORAL SENSATION AND COMPRISING PARTICLES WITH AN ACTIVE PRINCIPLE | LOSAN PHARMA GMBH (DE) | 2008-02-21 | — | — | WO | disclosed |