Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SCN1A | P35498 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3398608 | 1.00 | KDM4E (0.48) | KDM4EL3MBTL1GAAMAPTRAB9A | |
| SCHEMBL28128027 | 1.00 | KDM4E (0.48) | KDM4EL3MBTL1GAAMAPTRAB9A | |
| SCHEMBL3402145 | 0.90 | TSHR (0.49) | KDM4ETSHRSCN4AALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL28128239 | 0.89 | TSHR (0.51) | KDM4ERAB9ATSHRSCN4AALDH1A1 | |
| Hydrochloric Acid SCHEMBL3402327 | 0.89 | TSHR (0.51) | KDM4ERAB9ATSHRSCN4AALDH1A1 | |
| SCHEMBL3397865 | 0.80 | SCN4A (0.50) | KDM4ETSHRSCN4AALDH1A1CYP1A2 | |
| SCHEMBL21601403 | 0.79 | KDM4E (0.61) | KDM4EL3MBTL1GAAMAPTRAB9A | |
| Hydrochloric Acid SCHEMBL21595745 | 0.78 | KDM4E (0.59) | KDM4EL3MBTL1GAAMAPTRAB9A | |
| SCHEMBL18870073 | 0.77 | KDM4E (0.55) | KDM4EL3MBTL1GAAMAPTRAB9A | |
| SCHEMBL18870074 | 0.77 | KDM4E (0.55) | KDM4EL3MBTL1GAAMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2247571-A2 | DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING OF AMINOALKANOLS AND THEIR USE | Uniwersytet Jagiellonski (PL) | 2010-11-10 | — | — | EP | claimed |
| WO-2009093916-A2 | DERIVATIVES OF AMINOALKANOLS, METHOD OF OBTAINING AMINOALKANOLS AND THEIR USE | UNIWERSYTET JAGIELLONSKI (PL) | 2009-07-30 | — | — | WO | claimed |