⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| T-4-Aminocrotonic Acid (Taca) SCHEMBL489325 | 1.00 | — | — | |
| T-4-Aminocrotonic Acid (Taca) SCHEMBL232135 | 1.00 | — | — | |
| T-4-Aminocrotonic Acid (Taca) SCHEMBL29669578 | 1.00 | — | — | |
| T-4-Aminocrotonic Acid (Taca) SCHEMBL6461161 | 0.97 | — | — | |
| T-4-Aminocrotonic Acid (Taca) SCHEMBL29953967 | 0.97 | — | — | |
| T-4-Aminocrotonic Acid (Taca) SCHEMBL14844317 | 0.85 | GABRR1 (0.73) | — | |
| T-4-Aminocrotonic Acid (Taca) SCHEMBL14844314 | 0.85 | GABRR1 (0.73) | — | |
| T-4-Aminocrotonic Acid (Taca) SCHEMBL27844261 | 0.82 | GABRR1 (0.67) | — | |
| SCHEMBL3656253 | 0.80 | — | — | |
| SCHEMBL3656255 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120025976-A | Method for differentiating hematopoietic stem/progenitor cells into granulocytes | 苏州血霁生物科技有限公司 | 2025-05-23 | — | — | CN | claimed |
| US-20250163379-A1 | METHOD FOR DIFFERENTIATING HEMATOPOIETIC STEM/PROGENITOR CELLS INTO NK CELLS | HEMACELL BIOTECHNOLOGY INC. (CN) | 2025-05-22 | — | — | US | claimed |
| US-20250019345-A1 | NEW CANNABINOID-GABAPENTINOID CONJUGATES AND USES THEREOF | LONDON PHARMACEUTICALS AND RESEARCH CORPORATION (CA) | 2025-01-16 | — | — | US | claimed |
| US-12161695-B2 | GABA A receptor agonists for treatment of disorders influenced by dysfunction BETA cells | DIAMYD MEDICAL AB (SE) | 2024-12-10 | — | — | US | claimed |
| CN-118786209-A | Method for differentiating hematopoietic stem/progenitor cells into NK cells | 苏州血霁生物科技有限公司 | 2024-10-15 | — | — | CN | claimed |
| EP-4430023-A1 | NEW CANNABINOID-GABAPENTINOID CONJUGATES AND USES THEREOF | London Pharmaceuticals and Research Corporation (CA) | 2024-09-18 | — | — | EP | claimed |
| WO-2023165503-A1 | METHOD FOR DIFFERENTIATING HEMATOPOIETIC STEM/PROGENITOR CELLS INTO NK CELLS | 苏州血霁生物科技有限公司 | 2023-09-07 | — | — | WO | claimed |
| WO-2023082003-A1 | NEW CANNABINOID-GABAPENTINOID CONJUGATES AND USES THEREOF | LONDON PHARMACEUTICALS AND RESEARCH CORPORATION (CA) | 2023-05-19 | — | — | WO | claimed |
| WO-2021062048-A2 | METHODS AND SYSTEMS FOR MODULATING HEPATIC GABA PRODUCTION OR RELEASE TO ALTER FOOD INTAKE IN MONOGASTRIC SPECIES | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2021-04-01 | — | — | WO | claimed |
| US-9371387-B2 | Composition for prevention or treatment of ischemic cardiac disease, comprising inhibitor against age-albumin synthesis or release of mononuclear phagocyte system cells as active ingredient | GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) | 2016-06-21 | — | — | US | claimed |
| US-20140234343-A1 | COMPOSITION FOR PREVENTION OR TREATMENT OF ISCHEMIC CARDIAC DISEASE, COMPRISING INHIBITOR AGAINST AGE-ALBUMIN SYNTHESIS OR RELEASE OF MONONUCLEAR PHAGOCYTE SYSTEM CELLS AS ACTIVE INGREDIENT | NSAGE CORP. (KR) | 2014-08-21 | — | — | US | claimed |
| WO-2012126472-A1 | GABA-C RECEPTOR AGONISTS OR ANTAGONISTS FOR USE IN THE TREATMENT OF VASCULAR DISEASES | AARHUS UNIVERSITET (DK) | 2012-09-27 | — | — | WO | claimed |
| US-7109149-B2 | Regulation of plant fertility by modulation of GABA levels in flowers | THE UNIVERSITY OF CHICAGO (US) | 2006-09-19 | — | — | US | claimed |
| EP-1416794-A4 | REGULATION OF PLANT FERTILITY BY MODULATION OF GABA LEVELS IN FLOWERS | UNIV CHICAGO (US) | 2005-06-01 | — | — | EP | claimed |
| US-20040177398-A1 | Regulation of plant fertility by modulation of GABA levels in flowers | CHICAGO, THE UNIVERSITY OF | 2004-09-09 | — | — | US | claimed |
| EP-1416794-A2 | REGULATION OF PLANT FERTILITY BY MODULATION OF GABA LEVELS IN FLOWERS | The University of Chicago (US) | 2004-05-12 | — | — | EP | claimed |
| WO-2003000039-A2 | REGULATION OF PLANT FERTILITY BY MODULATION OF GABA LEVELS IN FLOWERS | UNIVERSITY OF CHICAGO (US) | 2003-01-03 | — | — | WO | claimed |
| CN-120025976-A | Method for differentiating hematopoietic stem/progenitor cells into granulocytes | 苏州血霁生物科技有限公司 | 2025-05-23 | — | — | CN | disclosed |
| US-4113867-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1978-09-12 | — | — | US | disclosed |
| US-4001411-A | ANTHELMINTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1977-01-04 | — | — | US | disclosed |