Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.58 |
| ▸ | PDE1C | Q14123 | 10/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | PDE8A | O60658 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | PDE9A | O76083 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394970 | 0.89 | GAA (0.69) | GAAPDE1CMEN1KMT2AALOX15 | |
| SCHEMBL3393426 | 0.87 | GAA (0.66) | GAAPDE1CMEN1KMT2AADORA2B | |
| SCHEMBL3394305 | 0.86 | GAA (0.60) | GAAPDE1CMEN1KMT2AADORA2B | |
| SCHEMBL13425621 | 0.86 | GAA (0.60) | GAAPDE1CMEN1KMT2AADORA2B | |
| SCHEMBL13426254 | 0.84 | GAA (0.62) | GAAPDE1CMEN1KMT2AADORA2B | |
| SCHEMBL3395671 | 0.84 | GAA (0.60) | GAAPDE1CMEN1KMT2AADORA2B | |
| SCHEMBL3397339 | 0.84 | GAA (0.60) | GAAPDE1CMEN1KMT2AADORA2B | |
| SCHEMBL3395597 | 0.84 | GAA (0.58) | GAAPDE1CMEN1KMT2AKDM4E | |
| SCHEMBL13426289 | 0.84 | GAA (0.81) | GAAPDE1CMEN1KMT2ATSHR | |
| SCHEMBL3395486 | 0.83 | GAA (0.57) | GAAPDE1CMEN1KMT2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |