SCHEMBL33978

SCHEMBL33978

COC1=C(O)C(=O)C(C)=C(O)C1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DUSP3 P51452 2/20 0.52
CDC25A P30304 2/20 0.40
CDC25B P30305 2/20 0.40
MAPT P10636 8/20 0.37
KDM4E B2RXH2 5/20 0.37
CYP2C19 P33261 3/20 0.37
MAPK1 P28482 3/20 0.37
TP53 P04637 2/20 0.37
HSD17B10 Q99714 1/20 0.37
APEX1 P27695 4/20 0.36
TDP1 Q9NUW8 6/20 0.35
LMNA P02545 3/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2D6 P10635 2/20 0.35
CYP2C9 P11712 2/20 0.35
PGR P06401 1/20 0.35
MAOA P21397 1/20 0.35
TBXA2R P21731 1/20 0.35
AVPR2 P30518 1/20 0.35
HTR2B P41595 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5158684 0.88 DUSP3 (0.42) DUSP3CDC25ACDC25BMAPTKDM4E
SCHEMBL9180312 0.88 DUSP3 (0.48) DUSP3CDC25ACDC25BMAPTKDM4E
SCHEMBL9175352 0.87 MAPT (0.42) DUSP3CDC25ACDC25BMAPTKDM4E
SCHEMBL21727072 0.79 MAPT (0.44) DUSP3CDC25ACDC25BMAPTKDM4E
SCHEMBL16309126 0.73 DUSP3 (0.68) DUSP3MAPTKDM4ECYP2C19MAPK1
SCHEMBL7287351 0.73 DUSP3 (0.68) DUSP3MAPTKDM4ECYP2C19MAPK1
SCHEMBL23271783 0.70 MAPT (0.53) DUSP3CDC25ACDC25BMAPTKDM4E
SCHEMBL30004043 0.70 MAPT (0.53) DUSP3CDC25ACDC25BMAPTKDM4E
SCHEMBL5818650 0.70 MAPT (0.38) DUSP3CDC25ACDC25BMAPTKDM4E
SCHEMBL1097952 0.69 DUSP3 (1.00) DUSP3MAPTKDM4ECYP2C19MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1828 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119979633-A Application of NADH kinase element sPos in improving yield of secondary metabolite of actinomycetes 中国农业科学院植物保护研究所 2025-05-13 CN claimed
EP-3727287-B1 HAIR DYEING PROCESS COMPRISING A STEP OF DYEING WITH HENNA AND/OR INDIGO AND A TREATMENT STEP COMPRISING THE APPLICATION OF A COMPOSITION COMPRISING A BUFFER SYSTEM OREAL (FR) 2024-12-04 EP claimed
US-12109297-B2 Process for treating keratin fibers employing an anhydride acrylic polymer in oily dispersion and an amine compound L'OREAL (FR) 2024-10-08 US claimed
US-20240261210-A1 PROCESS FOR TREATING KERATIN FIBERS EMPLOYING AN ANHYDRIDE ACRYLIC POLYMER IN OILY DISPERSION AND AN AMINE COMPOUND L'OREAL (FR) 2024-08-08 US claimed
EP-3989915-A1 OILY DISPERSION COMPRISING A POLYMERIC PARTICLE AND A STABILIZER BEARING A C9-C22 ALKYL GROUP, AND PROCESS FOR TREATING KERATIN MATERIALS USING THE OILY DISPERSION L'OREAL (FR) 2022-05-04 EP claimed
EP-3863593-A1 PROCESS FOR TREATING KERATIN FIBERS EMPLOYING AN ANHYDRIDE ACRYLIC POLYMER IN OILY DISPERSION AND AN AMINE COMPOUND L'OREAL (FR) 2021-08-18 EP claimed
WO-2020260659-A1 OILY DISPERSION COMPRISING A POLYMERIC PARTICLE AND A STABILIZER BEARING A C9-C22 ALKYL GROUP, AND PROCESS FOR TREATING KERATIN MATERIALS USING THE OILY DISPERSION L'OREAL (FR) 2020-12-30 WO claimed
EP-3727287-A1 HAIR DYEING PROCESS COMPRISING A STEP OF DYEING WITH HENNA AND/OR INDIGO AND A TREATMENT STEP COMPRISING THE APPLICATION OF A COMPOSITION COMPRISING A BUFFER SYSTEM L'OREAL (FR) 2020-10-28 EP claimed
EP-2400946-B1 COMPOSITION CONTAINING A DYE AND 3-PHENYL-1-PROPANOL AND DYEING OF KERATIN FIBRES OREAL (FR) 2018-10-24 EP claimed
EP-2654682-B1 HAIR DYEING PROCESS USING AN INSOLUBLE SILICATE, AN AROMATIC COMPOUND AND A HYDROXYLATED ALIPHATIC SOLVENT OREAL (FR) 2018-10-17 EP claimed
US-20030159221-A1 Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent L'OREAL S.A. (FR) 2003-08-28 US claimed
WO-2003042199-A1 AGENT AND METHOD FOR COLORING KERATIN FIBERS CONTAINING 2-BENZOTHIAZOLINONE-HYDRAZONE AND QUINONE DERIVATIVES WELLA AKTIENGESELLSCHAFT (DE) 2003-05-22 WO claimed
WO-2003030841-A1 METHOD FOR DYEING KERATINOUS FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2003-04-17 WO claimed
US-6458168-B1 Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative L'OREAL S.A. (FR) 2002-10-01 US claimed
US-6451067-B1 HAIR DYE MIXTURE L'OREAL S.A. (FR) 2002-09-17 US claimed
EP-0498707-B1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent OREAL (FR) 1995-08-02 EP claimed
EP-0498707-A1 Process of dyeing keratinous fibers with a mono- or di-hydroxyindole and a non-oxidative aromatic carbonyl derivative and dyeing agent L'OREAL (FR) 1992-08-12 EP claimed
US-5064442-A HAIR DYES L'OREAL (FR) 1991-11-12 US claimed
US-4971596-A COPPER, COBALT, IRON OR SILVER SALTS WITH QUINONE DYES L'OREAL (FR) 1990-11-20 US claimed
US-4832943-A HYDROXYQUINONE, MESOTARTARALDEHYDE L'OREAL (FR) 1989-05-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030159221-A1 Oxidation dyeing composition for keratinous fibres with a particular paraphenylene-diamine derivative and a particular direct dyeing agent KRT18, CDC73, DAO DUSP3 3565/4885CDC25A 3592/4885CDC25B 3552/4885
US-12109297-B2 Process for treating keratin fibers employing an anhydride acrylic polymer in oily dispersion and an amine compound KRT18, AURKA, AURKC DUSP3 4162/4885CDC25A 2110/4885CDC25B 1490/4885
US-20240261210-A1 PROCESS FOR TREATING KERATIN FIBERS EMPLOYING AN ANHYDRIDE ACRYLIC POLYMER IN OILY DISPERSION AND AN AMINE COMPOUND KRT18, AURKA, AURKC DUSP3 4162/4885CDC25A 2110/4885CDC25B 1490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.