Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363455 | 0.80 | CYP1A1 (0.47) | RELAHSP90AA1HSP90AB1TUBB1TUBB4A | |
| SCHEMBL6158612 | 0.78 | HSP90AA1 (0.50) | NQO2RELAHSP90AA1HSP90AB1NFE2L2 | |
| SCHEMBL23923708 | 0.78 | HSP90AA1 (0.52) | NQO2RELAHSP90AA1HSP90AB1TUBB1 | |
| SCHEMBL23923707 | 0.78 | HSP90AA1 (0.52) | NQO2RELAHSP90AA1HSP90AB1TUBB1 | |
| SCHEMBL2284577 | 0.75 | PDE4A (0.44) | HSP90AA1HSP90AB1TUBB1TUBB4ATUBB | |
| SCHEMBL1162277 | 0.74 | HSP90AA1 (0.49) | NQO2RELAHSP90AA1HSP90AB1NFE2L2 | |
| SCHEMBL20573442 | 0.74 | HSP90AA1 (0.52) | RELAHSP90AA1HSP90AB1NFE2L2CYP1A1 | |
| SCHEMBL14363441 | 0.74 | CYP1A1 (0.73) | NQO2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL28672446 | 0.74 | ABCG2 (0.47) | NQO2HSP90AA1HSP90AB1TUBB1TUBB4A | |
| SCHEMBL28672448 | 0.74 | ABCG2 (0.47) | NQO2HSP90AA1HSP90AB1TUBB1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245019-A1 | 4, 5-DIHYDRO-OXAZOL-2-YL AMINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2010-11-03 | — | — | EP | disclosed |
| WO-2009103626-A1 | 4, 5-DIHYDRO-OXAZOL-2-YL AMINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2009-08-27 | — | — | WO | disclosed |