Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 20/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4411050 | 0.99 | GSK3B (0.42) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL3398094 | 0.86 | GSK3B (0.39) | GSK3BCYP2D6CYP1A2 | |
| SCHEMBL3396964 | 0.85 | GSK3B (0.46) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| Hydrochloric Acid SCHEMBL4411055 | 0.84 | GSK3B (0.45) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL4380719 | 0.83 | GSK3B (0.44) | GSK3BCYP2D6 | |
| SCHEMBL3397060 | 0.83 | GSK3B (0.46) | GSK3BCYP2D6CYP1A2CSNK1A1GSK3A | |
| SCHEMBL3659663 | 0.81 | GSK3B (0.51) | GSK3B | |
| SCHEMBL3658703 | 0.81 | GSK3B (0.53) | GSK3BCYP2D6 | |
| SCHEMBL3891480 | 0.76 | GSK3B (0.46) | GSK3BCYP2D6 | |
| SCHEMBL3398498 | 0.76 | GSK3B (0.38) | GSK3BCYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501728-B2 | Substituted heteroarylamide oxazepinopyrimidone derivatives | SANOFI (FR) | 2013-08-06 | — | — | US | claimed |
| EP-2247598-B1 | SUBSTITUTED HETEROARYLAMIDE OXAZEPINOPYRIMIDONE DERIVATIVES | SANOFI SA (FR) | 2012-10-24 | — | — | EP | claimed |
| EP-2247598-A1 | SUBSTITUTED HETEROARYLAMIDE OXAZEPINOPYRIMIDONE DERIVATIVES | Sanofi-Aventis (FR) | 2010-11-10 | — | — | EP | claimed |
| WO-2009095787-A1 | SUBSTITUTED HETEROARYLAMIDE OXAZEPINOPYRIMIDONE DERIVATIVES | SANOFI-AVENTIS (FR) | 2009-08-06 | — | — | WO | claimed |
| EP-2085400-A1 | Substituted heteroarylamide oxazepinopyrimidone derivatives | Sanofi-Aventis (FR) | 2009-08-05 | — | — | EP | claimed |
| EP-2247598-B1 | SUBSTITUTED HETEROARYLAMIDE OXAZEPINOPYRIMIDONE DERIVATIVES | SANOFI SA (FR) | 2012-10-24 | — | — | EP | disclosed |
| EP-2247598-A1 | SUBSTITUTED HETEROARYLAMIDE OXAZEPINOPYRIMIDONE DERIVATIVES | Sanofi-Aventis (FR) | 2010-11-10 | — | — | EP | disclosed |
| WO-2009095787-A1 | SUBSTITUTED HETEROARYLAMIDE OXAZEPINOPYRIMIDONE DERIVATIVES | SANOFI-AVENTIS (FR) | 2009-08-06 | — | — | WO | disclosed |
| EP-2085400-A1 | Substituted heteroarylamide oxazepinopyrimidone derivatives | Sanofi-Aventis (FR) | 2009-08-05 | — | — | EP | disclosed |