Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CALML3 | P27482 | 1/20 | 0.41 |
| ▸ | SDHA | P31040 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3395820 | 0.92 | MAOB (0.45) | HRH4MAOBKMT2AMEN1MAOA | |
| SCHEMBL3394125 | 0.84 | MEN1 (0.46) | HRH4MAOBKMT2AMEN1MAOA | |
| SCHEMBL3398183 | 0.84 | MAOB (0.54) | MAOBKMT2AMEN1MAOALMNA | |
| SCHEMBL3392358 | 0.81 | MAOB (0.48) | MAOBKMT2AMEN1MAOALMNA | |
| SCHEMBL3392294 | 0.81 | MAOB (0.46) | MAOBKMT2AMEN1MAOALMNA | |
| SCHEMBL3394919 | 0.81 | MAOB (0.56) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL3395068 | 0.81 | MAOB (0.51) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL3397361 | 0.81 | MAOB (0.53) | MAOBMAOALMNAPTGS1CALML3 | |
| SCHEMBL3394854 | 0.80 | MAOB (0.47) | MAOBKMT2AMEN1MAOALMNA | |
| SCHEMBL3398179 | 0.80 | MAOB (0.55) | HRH4MAOBMAOALMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234390-A1 | NOVEL COMPOUND AND THEIR USE | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2010-09-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234390-A1 | NOVEL COMPOUND AND THEIR USE | HTRA1, PRSS1, PRNP | HRH4 131/4885MAOB 2054/4885KMT2A 4400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.