Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.64 |
| ▸ | EGFR | P00533 | 12/20 | 0.59 |
| ▸ | KDR | P35968 | 8/20 | 0.59 |
| ▸ | BRAF | P15056 | 3/20 | 0.59 |
| ▸ | LCK | P06239 | 2/20 | 0.59 |
| ▸ | RET | P07949 | 2/20 | 0.59 |
| ▸ | MET | P08581 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | LTK | P29376 | 2/20 | 0.59 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.59 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.59 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.59 |
| ▸ | CIT | O14578 | 1/20 | 0.59 |
| ▸ | GAK | O14976 | 1/20 | 0.59 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.59 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.59 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2163578 | 0.99 | SRC (0.63) | SRCEGFRKDRBRAFLCK | |
| Hydrochloric Acid SCHEMBL2163832 | 0.91 | EGFR (0.57) | SRCEGFRKDRRETEPHB4 | |
| Hydrochloric Acid SCHEMBL2163725 | 0.90 | SRC (0.62) | SRCEGFRKDRBRAFLCK | |
| Hydrochloric Acid SCHEMBL2163561 | 0.89 | SRC (0.66) | SRCEGFRKDRBRAFLCK | |
| Hydrochloric Acid SCHEMBL2165383 | 0.88 | EGFR (0.63) | SRCEGFRKDRBRAFLCK | |
| Hydrochloric Acid SCHEMBL2163075 | 0.85 | SRC (0.59) | SRCEGFRKDRBRAFLCK | |
| SCHEMBL2163611 | 0.85 | EGFR (0.81) | SRCEGFRKDRBRAFLCK | |
| Hydrochloric Acid SCHEMBL2164655 | 0.84 | EGFR (0.79) | SRCEGFRKDRBRAFLCK | |
| Hydrochloric Acid SCHEMBL2163789 | 0.84 | EGFR (0.63) | SRCEGFRKDRBRAFLCK | |
| Hydrochloric Acid SCHEMBL2164558 | 0.84 | SRC (0.67) | SRCEGFRKDRBRAFLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2251332-A1 | THE AROMATIC RING TRIAZINE DERIVATIVES AND THE USES THEREOF | Shenyang Pharmaceutical University (CN) | 2010-11-17 | — | — | EP | claimed |