Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3215220 | 1.00 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL3151040 | 0.88 | KCNH2 (0.62) | KCNH2 | |
| SCHEMBL3214151 | 0.87 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL3214159 | 0.87 | KCNH2 (0.48) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3145665 | 0.87 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL4611499 | 0.85 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL3220119 | 0.85 | KCNH2 (0.49) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3612006 | 0.83 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL3153796 | 0.82 | KCNH2 (0.73) | KCNH2 | |
| SCHEMBL13070860 | 0.81 | KCNH2 (0.72) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2136807-B1 | PYRROLO (3, 2, 1-IJ) QUINOLINE-4-ONE DERIVATIVES FOR TREATING TUBERCULOSIS | GLAXO GROUP LTD (GB) | 2010-11-03 | — | — | EP | claimed |
| EP-1980251-A1 | Pyrrolo[3,2,1-ij]quinoline-4-one derivatives for treating tuberculosis | GLAXO GROUP LIMITED (GB) | 2008-10-15 | — | — | EP | claimed |
| EP-1980251-A1 | Pyrrolo[3,2,1-ij]quinoline-4-one derivatives for treating tuberculosis | GLAXO GROUP LIMITED (GB) | 2008-10-15 | — | — | EP | disclosed |